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Volume 82, Issue 1
Received, 1st July, 2010, Accepted, 27th July, 2010, Published online, 29th July, 2010. |
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| Enantioselective Synthesis of the C(2)-C(11) Cyclopropylfuran Segment of Pinnatin A |
Masayoshi Tsubuki,* Terunobu Abekura, Kazunori Takahashi, and Toshio Honda*
Research Centre of Medicinal Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan |
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Abstract
Synthesis of the C(2)-C(11) segment, cyclopropylfuran derivative, of pinnatin A was accomplished by Suzuki cross-coupling between chiral cyclopropylboronic acid and bromofuran as a key step. Addition of silver (I) oxide was found to promote the Suzuki cross-coupling reactions. |
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Graphical Abstract
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| Corresponding author; email: tsubuki@hoshi.ac.jp |
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