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Communication | Regular issue | Vol 48, No. 2, 1998, pp.239-242
Published online:
DOI: 10.3987/COM-97-8056
Concise and Versatile Syntheses of N-Arylalkylpiperidines as Potential Intermediates for 4-Anilidopiperidine Analgesics

Young-Ger Suh,* Dong-Yun Shin, Kyung-Ho Cho, and Jae-Sang Ryu

*College of Pharmacy, Seoul National University, Shillim-Dong, San 56-1, Kwanak-Gu, Seoul 151-742, Korea

Abstract

N-Arylalkylpiperidones and N-arylalkylspiroepoxypiperidine as potential intermediates for 4-anilidopiperidine analgesics and their structural analogues have been efficiently synthesized from the simple arylalkylamines by two and three step sequences respectively.

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