Heterocycles Database
Natural Products with
Heterocyclic Ring System
 
 1975-2014
 58,387 Compounds
 25 April, 2012
 
Search by:
Name
Group

Carbon:
Carbon
Molecular Weight
Name
Group

Molecular Fomula:

Molecular Weight:

Author:
Author
Group

Journal:
Journal
Year
 
 Nomenclature :
 
The natural products are listed under the name used in the original literature.
 
 The abbreviations :
 
The following abbreviations have been used :
 
act : biological activity
cd : circular dichroism
Cnmr : 13C-nuclear magnetic resonance spectrum
Hnmr : 1H-nuclear magnetic resonance spectrum
ir : infrared spectrum
mass : mass spectrum
syn : total synthesis
uv : ultraviolet spectrum
 
 Journals :
 
This database lists the natural products with heterocyclic ring system whose structure has been determined since 1975.
The journals which have been covered are as follows.
 
Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi
 
 Editor :
 
Editor
Keiichiro Fukumoto

Associate Editor
Kunio Ogasawara
Yoshiharu Iwabuchi

Assistant Editors
Naoki Kanoh
Muneo Kawasumi
Takashi Moriya
Keiichi Murakami
Kohei Sakanishi
Yusuke Sasano
Takuro Shibuta
Masatoshi Shibuya

Editorial Assistants
Sayaka Kametani
Kishiko Nakano
Yuki Shima
Kazuko Todoroki
Michi Yamamoto
 New Heterocyclic Natural Products
This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.
 
25 April, 2012
Search by Group:
Polyketides
Aromatics
Terpenes
Steroids
Alkaloids
Antibiotics
Miscellaneous
 
All
 
Search by Journal :
Vol.
No.
Chem. Pharm. Bull.
59
9
Eur. J. Org. Chem.
26
Helv. Chim. Acta
94
9
Heterocycles
83
9
J. Med. Chem.
54
17
J. Nat. Prod.
74
9
Org. Lett.
13
17, 18
Planta medica
77
13, 14
Tetrahedron
67
35, 36, 37, 38, 39
Tetrahedron Lett.
52
36, 39
  141 data found. 1 - 30 listed Next Last   

Polyketides
No Name
C13H18O5 = 254
Tetrahedron    2014, 70 , 2129
J. Kornsakulkarn, S. Saepua, S. Komwijit, P. Rachtawee, C. Thongpanchang
DOI: 10.1016/j.tet.2014.02.004
CrossRef
 
[NS]  Astrocystis species BCC 22166
[mp]
[bp]
[α]D      + 6.6°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
No Name
C17H18O10 = 382
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      − 0.5°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
Mangromicin B
C22H32O6 = 392
J. Antibiot.    2014, 67 , 253
T. Nakashima, M. Iwatsuki, J. Ochiai, Y. Kamiya, K. Nagai, A. Matsumoto, A. Ishiyama, K. Otoguro, K. Shiomi, Y. Takahashi, S. Ōmura
DOI: 10.1038/ja.2013.129
CrossRef
 
[NS]  Lechevalieria aerocolonigenes K10-0216
[mp]
[bp]
[α]D      – 24.08°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antitrypanosomal activity

Polyketides
No Name
C18H20O10 = 396
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      + 6.8°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
Mangromicin A
C22H34O7 = 410
J. Antibiot.    2014, 67 , 253
T. Nakashima, M. Iwatsuki, J. Ochiai, Y. Kamiya, K. Nagai, A. Matsumoto, A. Ishiyama, K. Otoguro, K. Shiomi, Y. Takahashi, S. Ōmura
DOI: 10.1038/ja.2013.129
CrossRef
 
[NS]  Lechevalieria aerocolonigenes K10-0216
[mp]
[bp]
[α]D      – 13.56°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antitrypanosomal activity

Polyketides
Biselyngbyolide B
C27H40O4 = 428
Chemistry Lett.    2014, 43 , 287
O. Ohno, A. Watanabe, M. Morita, K. Suenaga
DOI: 10.1246/cl.130960
CrossRef
 
[NS]  Lyngbya species
[mp]
[bp]
[α]D      - 240°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]apoptosis-inducing and ER stress-inducing activities

Polyketides
No Name
C26H24O13 = 544
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      + 107.2°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
No Name
C27H26O13 = 558
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      + 150.6°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
No Name
C35H30O16 = 706
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      − 180.1°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
No Name
C36H32O16 = 720
J. Nat. Prod.    2014, 77 , 509
J. Zhao, S. I. Khan, M. Wang, Y. Vasquez, M. H. Yang, B. Avula, Y.-H. Wang, C. Avonto, T. J. Smillie, I. A. Khan
DOI: 10.1021/np400780n
CrossRef
 
[NS]  Chamaemelum nobile
[mp]
[bp]
[α]D      − 165.8°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]activities against inflammation and
metabolic disorder

Polyketides
Venturicidin C
C42H69NO11 = 763
J. Antibiot.    2014, 67 , 223
K. A. Shaaban, S. Singh, S. I. Elshahawi, X. Wang, L. V. Ponomareva, M. Sunkara, G. C. Copley, J. C. Hower, A. J. Morris, M. K. Kharel, J. S. Thorson
DOI: 10.1038/ja.2013.113
CrossRef
 
[NS]  Streptomyces species TS-2-2
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antifungal activity

Aromatics
No Name
C11H12O5 = 224
Tetrahedron    2014, 70 , 2129
J. Kornsakulkarn, S. Saepua, S. Komwijit, P. Rachtawee, C. Thongpanchang
DOI: 10.1016/j.tet.2014.02.004
CrossRef
 
[NS]  Astrocystis species BCC 22166
[mp]110.0 - 112.0 ℃
[bp]
[α]D      - 132.9°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic activity

Aromatics
Mellein, 7-Chloro-4-hydroxy-
C10H9O4Cl = 228.5
Helv. Chim. Acta    2014, 97 , 334
C.-H. Lu, S.-S. Liu, J.-Y. Wang, M.-Z. Wang, Y.-M. Shen
DOI: 10.1002/hlca.201300101
CrossRef
 
[NS]  Tubercularia species TF5
[mp]
[bp]
[α]D      + 20°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]
Notes:mixture with C4 epimer

Aromatics
Mellein, 7-Chloro-5-hydroxy-
C10H9O4Cl = 228.5
Helv. Chim. Acta    2014, 97 , 334
C.-H. Lu, S.-S. Liu, J.-Y. Wang, M.-Z. Wang, Y.-M. Shen
DOI: 10.1002/hlca.201300101
CrossRef
 
[NS]  Tubercularia species TF5
[mp]
[bp]
[α]D      + 12°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
No Name
C12H14O5 = 238
Tetrahedron    2014, 70 , 2129
J. Kornsakulkarn, S. Saepua, S. Komwijit, P. Rachtawee, C. Thongpanchang
DOI: 10.1016/j.tet.2014.02.004
CrossRef
 
[NS]  Astrocystis species BCC 22166
[mp]131.5 - 132.5 ℃
[bp]
[α]D      - 35.2°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic activity

Aromatics
Hoaensifuranonal
C15H14O3 = 242
Phytochemistry    2014, 99 , 121
S. Wittayalai, C. Mahidol, V. Prachyawarakorn, H. Prawat, S. Ruchirawat
DOI: 10.1016/j.phytochem.2013.12.017
CrossRef
 
[NS]  Drypetes hoaensis
[mp]
[bp]
[α]D      + 199.7°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic activity

Aromatics
Hoaensibenzofuranal
C15H16O3 = 244
Phytochemistry    2014, 99 , 121
S. Wittayalai, C. Mahidol, V. Prachyawarakorn, H. Prawat, S. Ruchirawat
DOI: 10.1016/j.phytochem.2013.12.017
CrossRef
 
[NS]  Drypetes hoaensis
[mp]
[bp]
[α]D      + 6.6°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic activity

Aromatics
No Name
C12H12O6 = 252
Tetrahedron    2014, 70 , 2129
J. Kornsakulkarn, S. Saepua, S. Komwijit, P. Rachtawee, C. Thongpanchang
DOI: 10.1016/j.tet.2014.02.004
CrossRef
 
[NS]  Astrocystis species BCC 22166
[mp]149.5 - 151.5 ℃
[bp]
[α]D      + 127.6°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antibacterial activity

Aromatics
No Name
C14H14O5 = 262
Heterocycles    2014, 89 , 731
L. Zhang, I. Hasegawa, T. Tatsuno, T. Kawabata, T. Ohta, T. Tadano
DOI: 10.3987/COM-13-12916
CrossRef
 
[NS]  Tabebuia avellanedae
[mp]
[bp]
[α]D      - 0.51°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
No Name
C16H12O6 = 300
Tetrahedron    2014, 70 , 1773
T. Sriyatep, S. Chakthong, S. Leejae, S. P. Voravuthikunchai
DOI: 10.1016/j.tet.2014.01.023
CrossRef
 
[NS]  Feroniella lucida
[mp]
[bp]
[α]D      - 23.0°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Damaurone D
C20H18O4 = 322
Helv. Chim. Acta    2014, 97 , 414
Y.-K. Li, J.-Q. Sun, X.-M. Gao, C. Lei
DOI: 10.1002/hlca.201300336
CrossRef
 
[NS]  Rosa damascena
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Damaurone E
C20H14O5 = 334
Helv. Chim. Acta    2014, 97 , 414
Y.-K. Li, J.-Q. Sun, X.-M. Gao, C. Lei
DOI: 10.1002/hlca.201300336
CrossRef
 
[NS]  Rosa damascena
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Damaurone C
C20H16O5 = 336
Helv. Chim. Acta    2014, 97 , 414
Y.-K. Li, J.-Q. Sun, X.-M. Gao, C. Lei
DOI: 10.1002/hlca.201300336
CrossRef
 
[NS]  Rosa damascena
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
No Name
C20H20O7 = 372
Heterocycles    2014, 89 , 731
L. Zhang, I. Hasegawa, T. Tatsuno, T. Kawabata, T. Ohta, T. Tadano
DOI: 10.3987/COM-13-12916
CrossRef
 
[NS]  Tabebuia avellanedae
[mp]
[bp]
[α]D      + 0.71°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Radicicol B
C18H19O7Cl = 382.5
J. Nat. Prod.    2014, 77 , 618
E. J. Mejia, S. T. Loveridge, G. Stepan, A. Tsai, G. S. Jones, T. Barnes, K. N. White, M. Drašković, K. Tenney, M. Tsiang, R. Geleziunas, T. Cihlar, N. Pagratis, Y. Tian, H. Yu, P. Crews
DOI: 10.1021/np400889x
CrossRef
 
[NS]  Humicola fuscoatra
[mp]
[bp]
[α]D      + 32°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]latent HIV-1 reactivation activity

Aromatics
Radicicol D
C18H19O7Cl = 382.5
J. Nat. Prod.    2014, 77 , 618
E. J. Mejia, S. T. Loveridge, G. Stepan, A. Tsai, G. S. Jones, T. Barnes, K. N. White, M. Drašković, K. Tenney, M. Tsiang, R. Geleziunas, T. Cihlar, N. Pagratis, Y. Tian, H. Yu, P. Crews
DOI: 10.1021/np400889x
CrossRef
 
[NS]  Humicola fuscoatra
[mp]
[bp]
[α]D      − 53°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Vitexkarinol
C20H18O8 = 386
J. Nat. Prod.    2014, 77 , 663
W. Pan, K. Liu, Y. Guan, G. T. Tan, N. V. Hung, N. M. Cuong, D. D. Soejarto, J. M. Pezzuto, H. H. S. Fong, H. Zhang
DOI: 10.1021/np400779v
CrossRef
 
[NS]  Vitex leptobotrys
[mp]
[bp]
[α]D      + 32.8°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Aromatics
Radicicol C
C18H21O8Cl = 400.5
J. Nat. Prod.    2014, 77 , 618
E. J. Mejia, S. T. Loveridge, G. Stepan, A. Tsai, G. S. Jones, T. Barnes, K. N. White, M. Drašković, K. Tenney, M. Tsiang, R. Geleziunas, T. Cihlar, N. Pagratis, Y. Tian, H. Yu, P. Crews
DOI: 10.1021/np400889x
CrossRef
 
[NS]  Humicola fuscoatra
[mp]
[bp]
[α]D      − 69°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Licorisoflavan C
C26H30O5 = 422
J. Nat. Prod.    2014, 77 , 521
J. R. Villinski, C. Bergeron, J. C. Cannistra, J. B. Gloer, C. M. Coleman, D. Ferreira, J. Azelmat, D. Grenier, S. Gafner
DOI: 10.1021/np400788r
CrossRef
 
[NS]  Glycyrrhiza uralensis
[mp]
[bp]
[α]D      + 18°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antibacterial activity

Aromatics
Caeruleanone C
C23H22O8 = 426
Org. Lett.    2014, 16 , 1462
L. B. Pérez, L. Pan, U. M. Acuña, J. Li, H.-B. Chai, J. C. Gallucci, T. N. Ninh, E. J. C. de Blanco, D. D. Soejarto, A. D. Kinghorn
DOI: 10.1021/ol500266z
CrossRef
 
[NS]  Millettia caerulea
[mp]
[bp]
[α]D      + 17.0°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]mitochondrial transmembrane potential inhibitory and quinone reductase induction activities

  141 data found. 1 - 30 listed Next Last   
   
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