Heterocycles Database
Natural Products with
Heterocyclic Ring System
 
 1975-2014
 58,387 Compounds
 25 April, 2012
 
Search by:
Name
Group

Carbon:
Carbon
Molecular Weight
Name
Group

Molecular Fomula:

Molecular Weight:

Author:
Author
Group

Journal:
Journal
Year
 
 Nomenclature :
 
The natural products are listed under the name used in the original literature.
 
 The abbreviations :
 
The following abbreviations have been used :
 
act : biological activity
cd : circular dichroism
Cnmr : 13C-nuclear magnetic resonance spectrum
Hnmr : 1H-nuclear magnetic resonance spectrum
ir : infrared spectrum
mass : mass spectrum
syn : total synthesis
uv : ultraviolet spectrum
 
 Journals :
 
This database lists the natural products with heterocyclic ring system whose structure has been determined since 1975.
The journals which have been covered are as follows.
 
Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi
 
 Editor :
 
Editor
Keiichiro Fukumoto

Associate Editor
Kunio Ogasawara
Yoshiharu Iwabuchi

Assistant Editors
Naoki Kanoh
Muneo Kawasumi
Takashi Moriya
Keiichi Murakami
Kohei Sakanishi
Yusuke Sasano
Takuro Shibuta
Masatoshi Shibuya

Editorial Assistants
Sayaka Kametani
Kishiko Nakano
Yuki Shima
Kazuko Todoroki
Michi Yamamoto
 New Heterocyclic Natural Products
This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.
 
25 April, 2012
Search by Group:
Polyketides
Aromatics
Terpenes
Steroids
Alkaloids
Antibiotics
Miscellaneous
 
All
 
Search by Journal :
Vol.
No.
Chem. Pharm. Bull.
59
9
Eur. J. Org. Chem.
26
Helv. Chim. Acta
94
9
Heterocycles
83
9
J. Med. Chem.
54
17
J. Nat. Prod.
74
9
Org. Lett.
13
17, 18
Planta medica
77
13, 14
Tetrahedron
67
35, 36, 37, 38, 39
Tetrahedron Lett.
52
36, 39
  212 data found. 1 - 30 listed Next Last   

Polyketides
Trichocladinol D
C11H14O5 = 226
J. Nat. Prod.    2014, 77 , 9
S. Chen, F. Ren, S. Niu, X. Liu, Y. Che
DOI: 10.1021/np4004799
CrossRef
 
[NS]  Trichocladium opacum
[mp]177 - 180 ℃
[bp]
[α]D      – 9.2°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Trichocladinol E
C11H14O5 = 226
J. Nat. Prod.    2014, 77 , 9
S. Chen, F. Ren, S. Niu, X. Liu, Y. Che
DOI: 10.1021/np4004799
CrossRef
 
[NS]  Trichocladium opacum
[mp]
[bp]
[α]D      – 13.7°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Trichocladinol F
C11H16O5 = 228
J. Nat. Prod.    2014, 77 , 9
S. Chen, F. Ren, S. Niu, X. Liu, Y. Che
DOI: 10.1021/np4004799
CrossRef
 
[NS]  Trichocladium opacum
[mp]158 - 161 ℃
[bp]
[α]D      – 1.5°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Trichocladinol G
C11H16O5 = 228
J. Nat. Prod.    2014, 77 , 9
S. Chen, F. Ren, S. Niu, X. Liu, Y. Che
DOI: 10.1021/np4004799
CrossRef
 
[NS]  Trichocladium opacum
[mp]135 - 138 ℃
[bp]
[α]D      – 2.2°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Trichocladinol H
C12H18O6 = 258
J. Nat. Prod.    2014, 77 , 9
S. Chen, F. Ren, S. Niu, X. Liu, Y. Che
DOI: 10.1021/np4004799
CrossRef
 
[NS]  Trichocladium opacum
[mp]
[bp]
[α]D      – 60.0°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Citrinoviric Acid
C14H20O6 = 284
Heterocycles    2014, 89 , 189
X. Hu, M.-W. Gong, W.-W. Zhang, Q.-H. Zheng, Q.-Y. Liu, L. Chen, Q.-Q. Zhang
DOI: 10.3987/COM-13-12874
CrossRef
 
[NS]  Trichoderma citrinoviride
[mp]
[bp]
[α]D      + 96.7°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic effect

Polyketides
Sweriledugenin A
C20H20O8 = 388
Org. Lett.    2014, 16 , 370
C.-A. Geng, X.-L. Chen, N.-J. Zhou, H. Chen, Y.-B. Ma, X.-Y. Huang, X.-M. Zhang, J.-J. Chen
DOI: 10.1021/ol403198d
CrossRef
 
[NS]  Swertia leducii
[mp]266 − 267 ℃
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]inhibiting HBV DNA replication
Notes:mixture of both enantiomers

Polyketides
Callyspongiolide
C33H42NO6Br = 628
Org. Lett.    2014, 16 , 266
C.-D. Pham, R. Hartmann, P. Böhler, B. Stork, S. Wesselborg, W. Lin, D. Lai, P. Proksch
DOI: 10.1021/ol403241v
CrossRef
 
[NS]  Callyspongia species
[mp]
[bp]
[α]D      - 12.5°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxicity against human Jurkat J16 T and Ramos B lymphocytes

Polyketides
Lobophorin H
C42H60N2O10 = 752
J. Antibiot.    2014, 67 , 121
Z. Lin, M. Koch, C. D. Pond, G. Mabeza, R. A. Seronay, G. P. Concepcion, L. R. Barrows, B. M. Olivera, E. W. Schmidt
DOI: 10.1038/ja.2013.115
CrossRef
 
[NS]  Streptomyces species 1053U.I.1a.3b
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Polyketides
Didemnaketal E
C46H74O16 = 882
Tetrahedron    2014, 70 , 35
G. A. Mohamed, S. R. M. Ibrahim, J. M. Badr, D. T. A. Youssef
DOI: 10.1016/j.tet.2013.11.057
CrossRef
 
[NS]  Didemnum species
[mp]
[bp]
[α]D      - 46.3°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]kinase inhibitory activity, antimicrobial activity

Polyketides
Didemnaketal D
C47H74O17 = 910
Tetrahedron    2014, 70 , 35
G. A. Mohamed, S. R. M. Ibrahim, J. M. Badr, D. T. A. Youssef
DOI: 10.1016/j.tet.2013.11.057
CrossRef
 
[NS]  Didemnum species
[mp]
[bp]
[α]D      - 51.9°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]kinase inhibitory activity, antimicrobial activity

Polyketides
Lobophorin I
C61H88N2O21 = 1184
J. Antibiot.    2014, 67 , 121
Z. Lin, M. Koch, C. D. Pond, G. Mabeza, R. A. Seronay, G. P. Concepcion, L. R. Barrows, B. M. Olivera, E. W. Schmidt
DOI: 10.1038/ja.2013.115
CrossRef
 
[NS]  Streptomyces species 1053U.I.1a.3b
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antimycobacterial activity, cytotoxicity

Polyketides
Calysolin V
C61H100O28 = 1281
Chem. Pharm. Bull.    2014, 62 , 97
M. Ono, A. Takigawa, Y. Kanemaru, G. Kawakami, K. Kabata, M.. Okawa, J. Kinjo, K. Yokomizo, H. Yoshimitsu, T. Nohara
DOI: 10.1248/cpb.c13-00610
CrossRef
 
[NS]  Calystegia soldanella
[mp]
[bp]
[α]D      − 16.5°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Polyketides
Calysolin VI
C61H102O28 = 1283
Chem. Pharm. Bull.    2014, 62 , 97
M. Ono, A. Takigawa, Y. Kanemaru, G. Kawakami, K. Kabata, M.. Okawa, J. Kinjo, K. Yokomizo, H. Yoshimitsu, T. Nohara
DOI: 10.1248/cpb.c13-00610
CrossRef
 
[NS]  Calystegia soldanella
[mp]
[bp]
[α]D      − 24.2°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Polyketides
Calysolin VII
C72H116O34 = 1525
Chem. Pharm. Bull.    2014, 62 , 97
M. Ono, A. Takigawa, Y. Kanemaru, G. Kawakami, K. Kabata, M.. Okawa, J. Kinjo, K. Yokomizo, H. Yoshimitsu, T. Nohara
DOI: 10.1248/cpb.c13-00610
CrossRef
 
[NS]  Calystegia soldanella
[mp]
[bp]
[α]D      − 54.0°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Polyketides
Calysolin IX
C72H120O34 = 1529
Chem. Pharm. Bull.    2014, 62 , 97
M. Ono, A. Takigawa, Y. Kanemaru, G. Kawakami, K. Kabata, M.. Okawa, J. Kinjo, K. Yokomizo, H. Yoshimitsu, T. Nohara
DOI: 10.1248/cpb.c13-00610
CrossRef
 
[NS]  Calystegia soldanella
[mp]
[bp]
[α]D      − 25.6°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Polyketides
Calysolin VIII
C72H120O34 = 1529
Chem. Pharm. Bull.    2014, 62 , 97
M. Ono, A. Takigawa, Y. Kanemaru, G. Kawakami, K. Kabata, M.. Okawa, J. Kinjo, K. Yokomizo, H. Yoshimitsu, T. Nohara
DOI: 10.1248/cpb.c13-00610
CrossRef
 
[NS]  Calystegia soldanella
[mp]
[bp]
[α]D      − 20.4°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiviral activity

Aromatics
No Name
C10H7NO3 = 189
Tetrahedron    2014, 70 , 869
S. Zhang, D.-B. Hu, J.-B. He, K.-Y. Guan, H.-J. Zhu
DOI: 10.1016/j.tet.2013.12.024
CrossRef
 
[NS]  Capparis spinosa
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Epicoccone B, 3-Methoxy-
C10H10O6 = 226
J. Nat. Prod.    2014, 77 , 49
M. E. Amrani, D. Lai, A. Debbab, A. H. Aly, K. Siems, C. Seidel, M. Schnekenburger, A. Gaigneaux, M. Diederich, D. Feger, W. Lin, P. Proksch
DOI: 10.1021/np4005745
CrossRef
 
[NS]  Epicoccum nigrum
[mp]
[bp]
[α]D      + 1.0°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Epicoccone, 3-Methoxy-
C10H10O6 = 226
J. Nat. Prod.    2014, 77 , 49
M. E. Amrani, D. Lai, A. Debbab, A. H. Aly, K. Siems, C. Seidel, M. Schnekenburger, A. Gaigneaux, M. Diederich, D. Feger, W. Lin, P. Proksch
DOI: 10.1021/np4005745
CrossRef
 
[NS]  Epicoccum nigrum
[mp]
[bp]
[α]D      + 0.8°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
No Name
C14H14O4 = 246
Heterocycles    2014, 89 , 183
G. Yang, W. Zhao, T. Zhang, Y. Duan, Z. Liu, M. Miao, Y. Chen
DOI: 10.3987/COM-13-12870
CrossRef
 
[NS]  Nicotiana tabacum
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]anti-TMV activity

Aromatics
No Name
C15H16O5 = 276
Heterocycles    2014, 89 , 183
G. Yang, W. Zhao, T. Zhang, Y. Duan, Z. Liu, M. Miao, Y. Chen
DOI: 10.3987/COM-13-12870
CrossRef
 
[NS]  Nicotiana tabacum
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]anti-TMV activity

Aromatics
No Name
C19H26O3 = 302
J. Nat. Prod.    2014, 77 , 22
C.-H. Chao, J.-C. Cheng, D.-Y. Shen, T.-S. Wu
DOI: 10.1021/np400528h
CrossRef
 
[NS]  Flueggea virosa
[mp]
[bp]
[α]D      + 54°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]anti-HCV activity

Aromatics
Paeoveitol
C19H20O5 = 328
Org. Lett.    2014, 16 , 424
W.-J. Liang, C.-A. Geng, X.-M. Zhang, H. Chen, C.-Y. Yang, G.-Q. Rong, Y. Zhao, H.-B. Xu, H. Wang, N.-J. Zhou, Y.-B. Ma, X.-Y. Huang, J.-J. Chen
DOI: 10.1021/ol403315d
CrossRef
 
[NS]  Paeonia veitchii
[mp]151 - 152 ℃
[bp]
[α]D      - 2.70°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
No Name
C17H18O7 = 334
Phytochemistry    2014, 97 , 81
G. C. Freitas, J. M. Batista Jr., G. C. Franchi Jr., A. E. Nowill, L. F. Yamaguchi, J. D. Vilcachagua, D. C. Favaro, M. Furlan, E. F. Guimarães, C. S. Jeffrey, M. J. Kato
DOI: 10.1016/j.phytochem.2013.10.012
CrossRef
 
[NS]  Piper carniconnectivum C. DC.
[mp]
[bp]
[α]D      + 166°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]cytotoxic

Aromatics
No Name
C22H28O3 = 340
J. Nat. Prod.    2014, 77 , 148
C. S. Jeffrey, M. D. Leonard, A. E. Glassmire, C. D. Dodson, L. A. Richards, M. J. Kato, L. A. Dyer
DOI: 10.1021/np400886s
CrossRef
 
[NS]  Piper kelleyi
[mp]
[bp]
[α]D
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]antiherbivore activity

Aromatics
No Name
C17H20O8 = 352
Phytochemistry    2014, 97 , 81
G. C. Freitas, J. M. Batista Jr., G. C. Franchi Jr., A. E. Nowill, L. F. Yamaguchi, J. D. Vilcachagua, D. C. Favaro, M. Furlan, E. F. Guimarães, C. S. Jeffrey, M. J. Kato
DOI: 10.1016/j.phytochem.2013.10.012
CrossRef
 
[NS]  Piper carniconnectivum C. DC.
[mp]183-186 ℃
[bp]
[α]D      + 92°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Saurufurin D
C20H20O6 = 356
J. Nat. Prod.    2014, 77 , 125
W.-J. Tsai, C.-C. Shen, T.-H. Tsai, L.-C. Lin
DOI: 10.1021/np400772h
CrossRef
 
[NS]  Saururus chinensis
[mp]
[bp]
[α]D      – 29°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Saurucinol K
C21H26O5 = 358
J. Nat. Prod.    2014, 77 , 100
H. Cui, B. Xu, T. Wu, J. Xu, Y. Yuan, Q. Gu
DOI: 10.1021/np400757k
CrossRef
 
[NS]  Saururus chinensis
[mp]
[bp]
[α]D      + 63°     [ CHCl3 ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]

Aromatics
Epicocconigrone A
C18H14O9 = 374
J. Nat. Prod.    2014, 77 , 49
M. E. Amrani, D. Lai, A. Debbab, A. H. Aly, K. Siems, C. Seidel, M. Schnekenburger, A. Gaigneaux, M. Diederich, D. Feger, W. Lin, P. Proksch
DOI: 10.1021/np4005745
CrossRef
 
[NS]  Epicoccum nigrum
[mp]
[bp]
[α]D      + 1.0°     [ MeOH ]
[Ph]
uv Hnmr Cnmr ir
Xray mass cd syn
[act]inhibitory activity of at least 15 protein kineses and histone deacetylase / cytostatic acivity

  212 data found. 1 - 30 listed Next Last   
   
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