|
Heterocycles Database
Natural Products with Heterocyclic Ring System |
 |
| |
| 1975-2010 |
| 53,681 Compounds |
|
25 January, 2010 |
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Search by:
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Carbon:
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Molecular Fomula:
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Molecular Weight:
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Author:
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Journal:
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| |
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| Nomenclature : |
| |
| The natural products are listed under the name used in the original literature. |
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| The abbreviations : |
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| The following abbreviations have been used : |
| |
| act : |
biological activity |
| cd : |
circular dichroism |
| Cnmr : |
13C-nuclear magnetic resonance spectrum |
| Hnmr : |
1H-nuclear magnetic resonance spectrum |
| ir : |
infrared spectrum |
| mass : |
mass spectrum |
| syn : |
total synthesis |
| uv : |
ultraviolet spectrum |
| |
| Journals : |
| |
This database lists the natural products with heterocyclic ring system whose structure has been determined since 1975.
The journals which have been covered are as follows. |
| |
Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi |
| |
| Editor : |
| |
Editor
Keiichiro Fukumoto
Associate Editor
Kunio Ogasawara
Yoshiharu Iwabuchi
Assistant Editors
Hayato Fukuda
Naoki Kanoh
Muneo Kawasumi
Yusuke Sasano
Masatoshi Sibuya
Hiroyuki Yamakoshi
Editorial Assistants
Kishiko Nakano
Sanae Ohura
Yuki Shima
Kazuko Todoroki
Michi Yamamoto
|
|
|
| New Heterocyclic Natural Products |
| This journal will list the new natural products with a heterocyclic ring
system, collected from current chemical literature, whose structure has been
established. |
| |
| 25 January, 2010 |
| | | Search by Journal : | Vol. | No. | | 48 | 24 | | 57 | 7 | | 2009 | 19 | | 92 | 7 | | 78 | 6,7 | | 62 | 7 | | 72 | 7 | | 11 | 13,14 | | 70 | 10 | | 65 | 23 | | 50 | 26,28-30 |  |  |  |
|  |  |  |
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| Polyketides R85573 |
| Fuligoic Acid |
C15H15O5Cl = 310.5
Tetrahedron Lett.
2009, 50 , 3189
A. Shintani, T. Ohtsuki,
Y. Yamamoto, T. Hakamatsuka,
N. Kawahara, Y. Goda, M. Ishibashi
DOI: 10.1016/j.tetlet.2009.01.122 CrossRef |
|
| [ | NS | ] | Fuligo septica f. flava |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 31° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Polyketides R85471 |
| Fusidilactone E |
C17H28O6 = 312
Eur. J. Org. Chem.
2009, , 3279
S. Qin, K. Krohn, U. Flörke,
B. Schulz, S. Draeger, G. Pescitelli,
P. Salvadori, S. Antus, T. Kurtán
|
|
| [ | NS | ] | Fusidium species |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
+ 1.3° [ CHCl3 ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | algicidal, antifungal, and antibacterial activities |
|
|
|
| Polyketides R85470 |
| Fusidilactone D |
C17H26O6 = 326
Eur. J. Org. Chem.
2009, , 3279
S. Qin, K. Krohn, U. Flörke,
B. Schulz, S. Draeger, G. Pescitelli,
P. Salvadori, S. Antus, T. Kurtán
|
|
| [ | NS | ] | Fusidium species |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
+ 37.3° [ CHCl3 ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | algicidal, antifungal, and antibacterial activities |
|
|
|
| Polyketides R85795 |
| Macarangioside F |
C19H32O8 = 388
Phytochemistry
2009, 70 , 1277
K. Matsunami, H. Otsuka, K. Kondo,
T. Shinzato, M. Kawahata,
K. Yamaguchi, Y. Takeda
DOI: 10.1016/j.phytochem.2009.07.020 CrossRef |
|
| [ | NS | ] | Macaranga tanarius |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 6.0° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Polyketides R85610 |
| Bistramide K, 39-Oxo- |
C40H68N2O8 = 704
J. Nat. Prod.
2009, 72 , 1338
B. T. Murphy, S. Cao, P. Brodie,
J. Maharavo,
H. Andriamanantoanina,
P. Ravelonandro, D. G. I. Kingston
DOI: 10.1021/np900072k CrossRef |
|
| [ | NS | ] | Trididemnum cyclops |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 72° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | antiproliferative activity |
|
|
|
| Aromatics R85620 |
| Alcyopterosin P |
C15H17O2Cl = 264.5
J. Nat. Prod.
2009, 72 , 1357
M. Carbone, L. Núñez-Pons,
F. Castelluccio, C. Avila,
M. Gavagnin
DOI: 10.1021/np900162t CrossRef |
|
| [ | NS | ] | Alcyonium grandis |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 822.9° [ CHCl3 ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85793 |
| No Name |
C15H17O4Cl = 296.5
Phytochemistry
2009, 70 , 1233
C. Kihampa, M. H. H. Nkunya,
C. C. Joseph, S. M. Magesa,
A. Hassanali, M. Heydenreich,
E. Kleinpeter
DOI: 10.1016/j.phytochem.2009.07.024 CrossRef |
|
| [ | NS | ] | Tessmannia densiflora |
| [ | mp | ] | 170 - 173 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85825 |
| No Name |
C18H14O5 = 310
Phytochemistry
2009, 70 , 1309
E. D. Coy-Barrera,
L. E. Cuca-Suárez,
M. Sefkow
DOI: 10.1016/j.phytochem.2009.07.010 CrossRef |
|
| [ | NS | ] | Ocotea macrophylla |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85709 |
| Xinjiastilbene B |
C21H22O3 = 322
Heterocycles
2009, 78 , 1581
N. Iwasaki, M. Baba, H. Aishan,
Y. Okada, T. Okuyama
DOI: 10.3987/COM-09-11673 CrossRef |
|
| [ | NS | ] | Glycyrrhiza inflata |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85829 |
| Albatrellutin |
C22H32O2 = 328
Heterocycles
2009, 78 , 1807
A.-L. Zhang, T. Xu, J.-M. Gao,
M.-S. Bai, G. Zhang, H.-W. Liu,
S.-Q. Li, Y. Konishi
DOI: 10.3987/COM-09-11675 CrossRef |
|
| [ | NS | ] | Albatrellus species |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 2° [ CHCl3 ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85607 |
| Communin A |
C23H18O3 = 342
J. Nat. Prod.
2009, 72 , 1335
P. Fu, S. Lin, L. Shan, M. Lu,
Y.-H. Shen, J. Tang, R.-H. Liu,
X. Zhang, R.-L. Zhu, W.-D. Zhang
DOI: 10.1021/np800830v CrossRef |
|
| [ | NS | ] | Polytrichum commune |
| [ | mp | ] | 212 - 213 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 52° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85608 |
| Communin B |
C23H18O3 = 342
J. Nat. Prod.
2009, 72 , 1335
P. Fu, S. Lin, L. Shan, M. Lu,
Y.-H. Shen, J. Tang, R.-H. Liu,
X. Zhang, R.-L. Zhu, W.-D. Zhang
DOI: 10.1021/np800830v CrossRef |
|
| [ | NS | ] | Polytrichum commune |
| [ | mp | ] | 247 - 250 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 47° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85827 |
| No Name |
C20H22O5 = 342
Phytochemistry
2009, 70 , 1309
E. D. Coy-Barrera,
L. E. Cuca-Suárez,
M. Sefkow
DOI: 10.1016/j.phytochem.2009.07.010 CrossRef |
|
| [ | NS | ] | Ocotea macrophylla |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
- 27.4° [ CHCl3 ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | PAF-antagonistic activity |
|
|
|
| Aromatics R85537 |
| Ugonin T |
C20H18O6 = 354
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 202 - 204 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 28.0° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | inhibitory activity against superoxide anion generation and elastase release |
|
|
|
| Aromatics R85826 |
| No Name |
C20H20O6 = 356
Phytochemistry
2009, 70 , 1309
E. D. Coy-Barrera,
L. E. Cuca-Suárez,
M. Sefkow
DOI: 10.1016/j.phytochem.2009.07.010 CrossRef |
|
| [ | NS | ] | Ocotea macrophylla |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85708 |
| Xinjiastilbene A |
C24H28O3 = 364
Heterocycles
2009, 78 , 1581
N. Iwasaki, M. Baba, H. Aishan,
Y. Okada, T. Okuyama
DOI: 10.3987/COM-09-11673 CrossRef |
|
| [ | NS | ] | Glycyrrhiza inflata |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85611 |
| No Name |
C17H20O9 = 368
J. Nat. Prod.
2009, 72 , 1341
J. Kornsakulkarn,
C. Thongpanchang, S. Lapanun,
K. Srichomthong
DOI: 10.1021/np900082h CrossRef |
|
| [ | NS | ] | Torrubiella tenuis BCC 12732 |
| [ | mp | ] | 191.7 - 193.0 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 63.41° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85523 |
| Sophoronol A |
C20H18O7 = 370
J. Nat. Prod.
2009, 72 , 1265
G.-P. Zhang, Z.-Y. Xiao,
J. Rafique, M. Arfan, P. J. Smith,
C. A. Lategan, L.-H. Hu
DOI: 10.1021/np900144c CrossRef |
|
| [ | NS | ] | Sophora mollis |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
+ 200° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85609 |
| Ohioensin H |
C23H16O5 = 372
J. Nat. Prod.
2009, 72 , 1335
P. Fu, S. Lin, L. Shan, M. Lu,
Y.-H. Shen, J. Tang, R.-H. Liu,
X. Zhang, R.-L. Zhu, W.-D. Zhang
DOI: 10.1021/np800830v CrossRef |
|
| [ | NS | ] | Polytrichum commune |
| [ | mp | ] | 270 - 272 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 22° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85612 |
| No Name |
C17H20O10 = 384
J. Nat. Prod.
2009, 72 , 1341
J. Kornsakulkarn,
C. Thongpanchang, S. Lapanun,
K. Srichomthong
DOI: 10.1021/np900082h CrossRef |
|
| [ | NS | ] | Torrubiella tenuis BCC 12732 |
| [ | mp | ] | 243.4 - 244.7 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 32.37° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85613 |
| No Name |
C17H20O10 = 384
J. Nat. Prod.
2009, 72 , 1341
J. Kornsakulkarn,
C. Thongpanchang, S. Lapanun,
K. Srichomthong
DOI: 10.1021/np900082h CrossRef |
|
| [ | NS | ] | Torrubiella tenuis BCC 12732 |
| [ | mp | ] | 242.3 - 242.8 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 11.05° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85469 |
| Sch1385568 |
C21H20O7 = 384
J. Antibiot.
2009, 62 , 401
S.-W. Yang, T.-M. Chan,
J. Terraciano, D. Loebenberg,
M. Patel, V. Gullo, M. Chu
DOI: 10.1038/ja.2009.51 CrossRef |
|
| [ | NS | ] | Aspergillus species SPRI-0814 |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
|
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | antifungal activity |
|
|
|
| Aromatics R85524 |
| Sophoronol B |
C21H20O8 = 400
J. Nat. Prod.
2009, 72 , 1265
G.-P. Zhang, Z.-Y. Xiao,
J. Rafique, M. Arfan, P. J. Smith,
C. A. Lategan, L.-H. Hu
DOI: 10.1021/np900144c CrossRef |
|
| [ | NS | ] | Sophora mollis |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
+ 159° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85526 |
| Sophoronol D |
C22H24O8 = 416
J. Nat. Prod.
2009, 72 , 1265
G.-P. Zhang, Z.-Y. Xiao,
J. Rafique, M. Arfan, P. J. Smith,
C. A. Lategan, L.-H. Hu
DOI: 10.1021/np900144c CrossRef |
|
| [ | NS | ] | Sophora mollis |
| [ | mp | ] | |
| [ | bp | ] | |
| [ | α | ]D |
+ 164° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85533 |
| Ugonin P |
C25H26O6 = 422
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 214 - 216 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
+ 55.3° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85536 |
| Ugonin S |
C25H26O6 = 422
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 223 - 225 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
+ 37.5° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | inhibitory activity against superoxide anion generation and elastase release |
|
|
|
| Aromatics R85532 |
| Ugonin O |
C25H22O7 = 434
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 234 - 236 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 19.8° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | inhibitory activity against superoxide anion generation and elastase release |
|
|
|
| Aromatics R85530 |
| Ugonin M |
C25H24O7 = 436
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 248 - 250 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
+ 79.6° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | inhibitory activity against superoxide anion generation and elastase release |
|
|
|
| Aromatics R85531 |
| Ugonin N |
C25H26O7 = 438
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 222 - 224 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
+ 14.9° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | |
|
|
|
| Aromatics R85534 |
| Ugonin Q |
C25H26O7 = 438
J. Nat. Prod.
2009, 72 , 1273
Y.-C. Huang, T.-L. Hwang,
C.-S. Chang, Y.-L. Yang,
C.-N. Shen, W.-Y. Liao,
S.-C. Chen, C.-C. Liaw
DOI: 10.1021/np900148a CrossRef |
|
| [ | NS | ] | Helminthostachys zeylanica |
| [ | mp | ] | 236 - 238 ℃ |
| [ | bp | ] | |
| [ | α | ]D |
- 38.0° [ MeOH ] |
| [ | Ph | ] |
uv
|
Hnmr
|
Cnmr
|
ir
|
Xray
|
mass
|
cd
|
syn
|
|
| [ | act | ] | inhibitory activity against superoxide anion generation and elastase release |
|
|
|
|
|