Heterocycles Database
Total Synthesis of
Heterocyclic
Natural Products
 
 1975-2014
 19,943 Compounds
 27 April, 2012
 
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 Nomenclature :
 
The natural products are listed under the name used in the original literature.
 
 Journals :
 
This database lists the natural products with heterocyclic ring system whose synthesis has been determined since 1975.
The journals which have been covered are as follows.
 
Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi
 
 Editor :
 
Editor
Keiichiro Fukumoto

Associate Editor
Kunio Ogasawara
Yoshiharu Iwabuchi

Assistant Editors
Naoki Kanoh
Muneo Kawasumi
Takashi Moriya
Keiichi Murakami
Kohei Sakanishi
Yusuke Sasano
Takuro Shibuta
Masatoshi Shibuya

Editorial Assistants
Sayaka Kametani
Kishiko Nakano
Yuki Shima
Kazuko Todoroki
Michi Yamamoto
 New Total Synthesis of Heterocyclic Natural Products
This journal will list natural products with heterocyclic ring system whose total synthesis has been reported.
 
27 April, 2012
Search by Group:
Polyketides
Aromatics
Terpenes
Steroids
Alkaloids
Antibiotics
Miscellaneous
 
All
 
Search by Journal :
Vol.
No.
Angew. Chem. Int. Ed.
50
37-40
Chem. Commun.
47
35, 36
Eur. J. Org. Chem.
2011
25, 26
J. Nat. Prod.
74
9
J. Org. Chem.
76
17
Org. Bio. Chem.
9
18
Org. Lett.
13
17, 18
Synlett
2011
14, 15
Synthesis
2011
17, 18
Tetrahedron
67
35, 36, 38, 39
Tetrahedron Lett.
52
36-38
  83 data found. 1 - 30 listed Next Last   

Polyketides
Frontalin
C8H14O2 = 142
Synlett    2014, 25 , 251
T. H. Kim, Y.-K. Kim, Z. Yang, J. W. Jung, L. S. Jeong, H.-D. Kim
DOI: 10.1055/s-0033-1340163
CrossRef
 
chiral
racemic
Notes:


Polyketides
Decytospolide A
C14H26O3 = 242
Chem. Eur. J.    2014, 20 , 405
J. Zeng, Y. J. Tan, J. Ma, M. L. Leow, D. Tirtorahardjo, X.-W. Liu
DOI: 10.1002/chem.201303328
CrossRef
 
chiral
racemic
Notes:


Polyketides
Cytospolide D
C15H26O4 = 270
Tetrahedron Asymmetry    2014, 25 , 148
A. Kamal, M. Balakrishna, P. V. Reddy, A. Rahim
DOI: 10.1016/j.tetasy.2013.12.004
CrossRef
 
chiral
racemic
Notes:


Polyketides
Decytospolide B
C16H28O4 = 284
Chem. Eur. J.    2014, 20 , 405
J. Zeng, Y. J. Tan, J. Ma, M. L. Leow, D. Tirtorahardjo, X.-W. Liu
DOI: 10.1002/chem.201303328
CrossRef
 
chiral
racemic
Notes:


Polyketides
Strictifolione
C19H24O4 = 316
Org. Lett.    2014, 16 , 122
S. Jayasinghe, P. K. M.Venukadasula, P. R. Hanson
DOI: 10.1021/ol403110p
CrossRef
 
chiral
racemic
Notes:


Polyketides
Synrotolide
C16H22O8 = 342
Eur. J. Org. Chem.    2014, , 455
G. Sabitha, A. S. Rao, A. Sandeep, J. S. Yadav
DOI: 10.1002/ejoc.201301215
CrossRef
 
chiral
racemic
Notes:


Polyketides
No Name
C21H28O4 = 344
Org. Lett.    2014, 16 , 122
S. Jayasinghe, P. K. M.Venukadasula, P. R. Hanson
DOI: 10.1021/ol403110p
CrossRef
 
chiral
racemic
Notes:


Polyketides
Murolic Acid
C21H36O5 = 368
Eur. J. Org. Chem.    2014, , 237
R. A. Fernandes, P. H. Patil, A. K. Chowdhury
DOI: 10.1002/ejoc.201301287
CrossRef
 
chiral
racemic
Notes:


Polyketides
Bermudenynol
C15H19O2BrCl2 = 382
Angew. Chem. Int. Ed.    2014, 53 , 272
G. Kim, T. Sohn, D. Kim, R. S. Paton
DOI: 10.1002/anie.201308077
CrossRef
 
chiral
racemic
Notes:


Polyketides
Eushearilide
C29H54NO6P = 543
Heterocycles    2014, 88 , 1175
T. Yamauchi, J. Takidaira, K. Okamoto, T. Sugiura, H. Horikoshi, S. Kudo, S. Sasaki, N. Mizushima, K. Higashiyama
DOI: 10.3987/COM-13-S(S)79
CrossRef
 
chiral
racemic
Notes: synthesis of proposed structure
synthesis of both C23 diastereomer


Polyketides
Angiolam A
C34H53NO7 = 587
Org. Lett.    2014, 16 , 548
M. T. Gieseler, M. Kalesse
DOI: 10.1021/ol403423r
CrossRef
 
chiral
racemic
Notes: revised the absolute configuration


Polyketides
Thuggacin B
C35H53NO7S = 631
Chem. Eur. J.    2014, 20 , 68
A. Matsuzawa, C. R. Opie, N. Kumagai, M. Shibasaki
DOI: 10.1002/chem.201304297
CrossRef
 
chiral
racemic
Notes:


Polyketides
Lasonolide A
C41H60O9 = 696
J. Am. Chem. Soc.    2014, 136 , 88
B. M. Trost, C. E. Stivala, K. L. Hull, A. Huang, D. R. Fandrick
DOI: 10.1021/ja411270d
CrossRef
 
chiral
racemic
Notes:


Polyketides
Pectenotoxin-2
C47H70O14 = 858
Angew. Chem. Int. Ed.    2014, 53 , 780
K. Fujiwara, Y. Suzuki, N. Koseki, Y. Aki, Y. Kikuchi, S. Murata, F. Yamamoto, M. Kawamura, T. Norikura, H. Matsue, A. Murai, R. Katoono, H. Kawai, T. Suzuki
DOI: 10.1002/anie.201308502
CrossRef
 
chiral
racemic
Notes:


Aromatics
No Name
C14H14O4 = 246
Heterocycles    2014, 88 , 939
J. Boukouvalas, V. Albert
DOI: 10.3987/COM-13-S(S)92
CrossRef
 
chiral
racemic
Notes:


Aromatics
Ribisin C
C14H14O5 = 262
Org. Lett.    2014, 16 , 228
P. Lan, M. G. Banwell, J. S. Ward, A. C. Willis
DOI: 10.1021/ol403220t
CrossRef
 
chiral
racemic
Notes: synthesis of both enantiomers


Aromatics
Altertenuol
C14H10O6 = 274
Heterocycles    2014, 89 , 59
T. Matsukihira, S. Saga, Y. Horino, H. Abe
DOI: 10.3987/COM-13-12859
CrossRef
 
chiral
racemic
Notes:


Aromatics
Frondosin B
C20H24O2 = 296
Chem. Eur. J.    2014, 20 , 253
D. R. Laplace, B. Verbraeken, K. V. Hecke, J. M. Winne
DOI: 10.1002/chem.201303273
CrossRef
 
chiral
racemic
Notes:


Aromatics
Centrolobine
C20H24O3 = 312
Chem. Eur. J.    2014, 20 , 405
J. Zeng, Y. J. Tan, J. Ma, M. L. Leow, D. Tirtorahardjo, X.-W. Liu
DOI: 10.1002/chem.201303328
CrossRef
 
chiral
racemic
Notes:


Aromatics
Antrodin A
C19H22O4 = 314
Heterocycles    2014, 88 , 939
J. Boukouvalas, V. Albert
DOI: 10.3987/COM-13-S(S)92
CrossRef
 
chiral
racemic
Notes:


Aromatics
Antrocinnamomin D
C19H24O4 = 316
Heterocycles    2014, 88 , 939
J. Boukouvalas, V. Albert
DOI: 10.3987/COM-13-S(S)92
CrossRef
 
chiral
racemic
Notes:


Aromatics
Liphagal
C22H28O4 = 356
Chem. Eur. J.    2014, 20 , 253
D. R. Laplace, B. Verbraeken, K. V. Hecke, J. M. Winne
DOI: 10.1002/chem.201303273
CrossRef
 
chiral
racemic
Notes: formal synthesis


Aromatics
Blechnic Acid, trans-
C18H14O8 = 358
Synlett    2014, 25 , 288
M. Ito, R. Namie, J. Krishnamurthi, H. Miyamae, K. Takeda, H. Nambu, S. Hashimoto
DOI: 10.1055/s-0033-1340291
CrossRef
 
chiral
racemic
Notes:


Aromatics
Uralenol
C20H18O7 = 370
Synthesis    2014, 46 , 170
T. Kawamura, M. Hayashi, R. Mukai, J. Terao, H. Nemoto
DOI: 10.1055/s-0033-1338559
CrossRef
 
chiral
racemic
Notes:


Aromatics
Ophiodilactone B
C34H28O5 = 516
Angew. Chem. Int. Ed.    2014, 53 , 757
T. Matsubara, K. Takahashi, J. Ishihara, S. Hatakeyama
DOI: 10.1002/anie.201307835
CrossRef
 
chiral
racemic
Notes:


Aromatics
Ophiodilactone A
C34H30O5 = 518
Angew. Chem. Int. Ed.    2014, 53 , 757
T. Matsubara, K. Takahashi, J. Ishihara, S. Hatakeyama
DOI: 10.1002/anie.201307835
CrossRef
 
chiral
racemic
Notes:


Aromatics
Procyanidin B1
C30H26O12 = 578
Heterocycles    2014, 88 , 1595
S. Ishihara, S. Doi, K. Harui, T. Okamoto, S. Okaomoto, J. Uenishi, T. Kawasaki, N. Nakajima, A. Saito
DOI: 10.3987/COM-13-S(S)103
CrossRef
 
chiral
racemic
Notes:


Aromatics
Saptomycin B
C41H52N2O9 = 716
Angew. Chem. Int. Ed.    2014, 53 , 1262
K. Kitamura, Y. Maezawa, Y. Ando, T. Kusumi, T. Matsumoto, K. Suzuki
DOI: 10.1002/anie.201308017
CrossRef
 
chiral
racemic
Notes:


Alkaloids
Retronecanol, Iso-
C8H15NO = 141
Tetrahedron    2014, 70 , 204
M. Brambilla, S. G. Davies, A. M. Fletcher, P. M. Roberts, J. E. Thomson
DOI: 10.1016/j.tet.2013.11.094
CrossRef
 
chiral
racemic
Notes:


Alkaloids
Trachelantamidine
C8H15NO = 141
Tetrahedron    2014, 70 , 204
M. Brambilla, S. G. Davies, A. M. Fletcher, P. M. Roberts, J. E. Thomson
DOI: 10.1016/j.tet.2013.11.094
CrossRef
 
chiral
racemic
Notes:


  83 data found. 1 - 30 listed Next Last   
   
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