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Abstract

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Paper | Regular issue | Vol 68, No. 8, 2006, pp.1669-1673
Published online: 27th June, 2006
DOI: 10.3987/COM-06-10785
A Simple KHSO4 Promoted Synthesis of 2-Arylsubstituted Benzimidazoles by Oxidative Condensation of Aldehydes with o-Phenylenediamine

Huiqiang Ma, Yulu Wang, and Jinye Wang*

*College of Chemistry and Environmental Science, Henan Normal University, Xinxiang, 453007, Henan, China

Abstract

KHSO4 is used to promote the oxidative condensation of o-phenylenediamine with aldehydes in DMF and afford corresponding 2-substituted benzimidazoles efficiently. Simple and convenient procedure, use of inexpensive promoter, easy purification and shorter reaction time are the advantageous features of this method.

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