HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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e-Journal
Abstract
1 data found. 1 - 1 listed
Paper | Regular issue | Vol 27, No. 5, 1988, pp. 1197 - 1205
Published online:
■ 1,4-Additions of Amines to 5-Methoxyfuran-1(5H)-one; an Efficient Synthesis of Amino Diols
Published online:
DOI: 10.3987/COM-87-4456
■ 1,4-Additions of Amines to 5-Methoxyfuran-1(5H)-one; an Efficient Synthesis of Amino Diols
Ben L. Feringa* and B. de Lange
*Department of Organic Chemistry, University of Groningen, Nijenborgh 16, 9747 AG Groningen, The Netherlands
Abstract
The 1,4-addition of various primary and secondary amines to 5-methoxyfuran-2(5H)-one in N,N-dimethylformamide or methylene chloride at room temperature affords quantitatively β-amino lactones 1a-g. The latter compounds are conveniently reduced to amino diols in high yields. Under similar conditions 1-(α)-methylbenzylamine gave optically active amino diols.
1 data found. 1 - 1 listed
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