e-Journal

Abstract

1 data found. 1 - 1 listed
Paper | Special issue | Vol 52, No. 1, 2000, pp. 325 - 332
Published online:
DOI: 10.3987/COM-99-S27
■ Phenanthridone Analogs of the Opiate Agonist U-47,700 in the trans-1,2-Diaminocyclohexane Benzamide Series

Shikai Zhao, Michael J. Totleben, Stephen A. Mizsak, Jeremiah P. Freeman, and Jacob Szmuszkovicz*

*Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, U.S.A.

Abstract

The first rigid analog of the opioid trans-1,2-diaminocyclohexane benzamide template was prepared. This analog represented by compound (4b), in a phenanthridone analog of the mu agonist U-47,700 which, historically, was the forerunner of the kappa acetamide U-50,488.

PDF (413KB)
1 data found. 1 - 1 listed