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Abstract

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Communication | Regular issue | Vol 26, No. 4, 1987, pp. 921 - 924
Published online:
DOI: 10.3987/R-1987-04-0921
Asymmetric α-Amidoalkylation. Synthesis of α-Substituted Piperidines of High Enantiomeric Purity

Klaus Th. Wanner and Annerose Kärtner

*Institut für Pharmazie und Lebensmittelchemie, Universität München, Sophienstraße 10, D-80333 München, Germany

Abstract

A stereoselective α-amidoalkylation was performed employing the chiral and cyclic enamide 1. The resulting amides 6 were employed in the synthesis of the title products.

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