HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
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e-Journal
Abstract
1 data found. 1 - 1 listed
Short Paper | Regular issue | Vol 91, No. 8, 2015, pp. 1668 - 1677
Published online: 6th July, 2015
Full Text HTMLPDF (338KB)PDF with Links (550KB)
Published online: 6th July, 2015
DOI: 10.3987/COM-15-13263
■ Preparation and Antibacterial Evaluation of Some Symmetrical Twin-Drug Type Bivalent Molecules
Fumiko Fujisaki, Makoto Furutachi, Ryou Fujiwara, Miriko Okabe, Hatsumi Aki, Nobuhiro Kashige, Fumio Miake, and Kunihiro Sumoto*
*Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan
Abstract
As one of our projects to investigate new bioactive compounds, we here report the synthesis and antibacterial evaluation of a few identical linker mode twin-drug type symmetrical hydantoin derivatives. The antibacterial activity of tested twin-drug type hydantoin derivatives (4~7) and the structure-activity relationships (SARs) of these bivalent symmetrical molecules are also described.
1 data found. 1 - 1 listed
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