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Review | Regular issue | Vol 91, No. 10, 2015, pp. 1863 - 1903
Published online: 5th October, 2015
DOI: 10.3987/REV-15-824
Ring Opening Ring Closure Reactions with 3-Substituted Chromones under Nucleophilic Conditions

Magdy A. Ibrahim,* Nasser M. El-Gohary, and Sara Said

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711, Egypt

Abstract

This review covers the ring opening ring closure (RORC) reactions of 3-substituted chromones with a variety of nitrogen and carbon nucleophiles. The nucleophilic reagent usually attack 3-substituted chromones at the C-2 position with γ-pyrone ring opening followed by further transformation during the course of the reaction producing a variety of products depending on the substrate at position 3, the nature of nucleophile and the reaction conditions.

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