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Review | Regular issue | Vol 94, No. 10, 2017, pp. 1819 - 1846
Published online: 27th July, 2017
DOI: 10.3987/REV-17-867
5-Aminotetrazole as a Building Block for Multicomponent Reactions (Review)

Anton V. Dolzhenko*

*School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor Darul Ehsan 47500, Malaysia

Abstract

5-Aminotetrazole is a useful building block in organic synthesis, including various multicomponent reactions (MCRs). In MCRs, 5-aminotetrazole usually plays a role of 1,3-binucleophilic reagent, but in some reactions, the only reactive centre is an exocyclic amino group of 5-aminotetrazole. This review systematises MCRs involving 5-aminotetrazole forming a background for further investigations in this area.

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