Natural Products with Heterocyclic Ring System

Synthesis

New Heterocyclic Natural Products

Updated: 26 December, 2018

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose synthesis has been established.

55 data found. 1 - 30 listed Next Last
Polyketides

Nicotlactone B

C13H14O5 = 234
Org. Biomol. Chem. 2018, 16, 1672
S. Henrion, A. Macé, M. M. Vallejos, T. Roisnel, B. Carboni, J. M. Villalgordo, F. Carreaux
DOI: 10.1039/C8OB00101D
CrossRef
chiral
racemic
Notes:
Polyketides

Pestalotioprolide C

C14H24O4 = 256
Synthesis 2018, 50, 1152
G. R. Kundoor, S. K. Battina, P. R. Krishna
DOI: 10.1055/s-0036-1589152
CrossRef
chiral
racemic
Notes:
Polyketides

Disparlure

C19H38O = 282
Org. Lett. 2018, 20, 1269
D. W. Klosowski, S. F. Martin
DOI: 10.1021/acs.orglett.7b03911
CrossRef
chiral
racemic
Notes:
Polyketides

Tanikolide

C17H32O3 = 284
Tetrahedron 2018, 74, 1059
H. Jinnouchi, H. Nambu, T. Fujiwara, T. Yakura
DOI: 10.1016/j.tet.2018.01.035
CrossRef
chiral
racemic
Notes:
Polyketides

Dolabriferol

C21H38O6 = 386
Europ. J. Org. Chem. 2018, , 1230
N. Gantasala, S. Borra, S. Pabbaraja
DOI: 10.1002/ejoc.201701748
CrossRef
chiral
racemic
Notes:
Polyketides

Iriomoteolide-2a

C32H52O7 = 548
Angew. Chem. Int. Ed. 2018, 57, 3801
K. Sakamoto, A. Hakamata, M. Tsuda, H. Fuwa
DOI: 10.1002/anie.201800507
CrossRef
chiral
racemic
Notes: revised structure
Aromatics

Urolithin B

C13H8O3 = 212
J. Org. Chem. 2018, 83, 3200
L. Zhang, Z. Zhang, J. Hong, J. Yu, J. Zhang, F. Mo
DOI: 10.1021/acs.joc.8b00089
CrossRef
chiral
racemic
Notes:
Aromatics

Eleutherol

C14H12O3 = 228
Synlett 2018, 29, 457
D. I. A. Othman, K. Otsuka, S. Takahashi, K. B. Selim, M. A. El-Sayed, A. S. Tantawy, T. Okauchi, M. Kitamura
DOI: 10.1055/s-0036-1589118
CrossRef
chiral
racemic
Notes:
Aromatics

Urolithin A

C13H8O4 = 228
J. Org. Chem. 2018, 83, 3200
L. Zhang, Z. Zhang, J. Hong, J. Yu, J. Zhang, F. Mo
DOI: 10.1021/acs.joc.8b00089
CrossRef
chiral
racemic
Notes:
Aromatics

Urolithin C

C13H8O5 = 244
J. Org. Chem. 2018, 83, 3200
L. Zhang, Z. Zhang, J. Hong, J. Yu, J. Zhang, F. Mo
DOI: 10.1021/acs.joc.8b00089
CrossRef
chiral
racemic
Notes:
Aromatics

Aureol

C21H30O2 = 314
Tetrahedron Lett. 2018, 59, 945
J.-L. Wang, H.-J. Li, M. Wang, J.-H. Wang, Y.-C. Wu
DOI: 10.1016/j.tetlet.2018.01.091
CrossRef
chiral
racemic
Notes:
Aromatics

Bussealin E

C18H18O6 = 330
Org. Lett. 2018, 20, 1597
D. G. Twigg, L. Baldassarre, E. C. Frye, W. R. J. D. Galloway, D. R. Spring
DOI: 10.1021/acs.orglett.8b00340
CrossRef
chiral
racemic
Notes:
Aromatics

Galbacin

C20H20O5 = 340
Org. Biomol. Chem. 2018, 16, 1672
S. Henrion, A. Macé, M. M. Vallejos, T. Roisnel, B. Carboni, J. M. Villalgordo, F. Carreaux
DOI: 10.1039/C8OB00101D
CrossRef
chiral
racemic
Notes:
Aromatics

Adunctin B

C26H30O4 = 406
J. Org. Chem. 2018, 83, 3392
D. H. Dethe, B. D. Dherange
DOI: 10.1021/acs.joc.8b00015
CrossRef
chiral
racemic
Notes:
Aromatics

Eleuthoside A

C20H22O9 = 406
Synlett 2018, 29, 457
D. I. A. Othman, K. Otsuka, S. Takahashi, K. B. Selim, M. A. El-Sayed, A. S. Tantawy, T. Okauchi, M. Kitamura
DOI: 10.1055/s-0036-1589118
CrossRef
chiral
racemic
Notes:
Aromatics

Berkelic Acid

C29H40O9 = 532
Tetrahedron 2018, 74, 909
C. F. Bender, C. L. Paradise, V. M. Lynch, F. K. Yoshimoto, J. K. D. Brabander
DOI: 10.1016/j.tet.2018.01.021
CrossRef
chiral
racemic
Notes:
Steroids

Aglatomin B

C22H34O4 = 362
Angew. Chem. Int. Ed. 2018, 57, 3617
J. Deng, J. Wu, H. Tian, J. Bao, Y. Shi, W. Tian, J. Gui
DOI: 10.1002/anie.201712365
CrossRef
chiral
racemic
Notes: proposed structure
Alkaloids

Allosedridine

C8H17NO = 143
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Sedridine

C8H17NO = 143
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

β-Conhydrine

C8H17NO = 143
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Ethylnorlobelol

C9H19NO = 157
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Ethylnorlobelol, 2’-epi-

C9H19NO = 157
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Halosaline

C10H21NO = 171
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Halosaline, 8-epi-

C10H21NO = 171
Synthesis 2018, 50, 1113
S. T. Bugde, P. S. Volvoikar, S. G. Tilve
DOI: 10.1055/s-0036-1589523
CrossRef
chiral
racemic
Notes:
Alkaloids

Indolizidine 209D

C14H27N = 209
Org. Lett. 2018, 20, 1439
H. E. Ho, M. J. James, P. O’Brien, R. J. K. Taylor, W. P. Unsworth
DOI: 10.1021/acs.orglett.8b00225
CrossRef
chiral
racemic
Notes:
Alkaloids

Tubifoline, Dehydro-

C18H20N2 = 264
Angew. Chem. Int. Ed. 2018, 57, 3806
W. He, J. Hu, P. Wang, L. Chen, K. Ji, S. Yang, Y. Li, Z. Xie, W. Xie
DOI: 10.1002/anie.201800567
CrossRef
chiral
racemic
Notes:
Alkaloids

Tubifoline

C18H22N2 = 266
Angew. Chem. Int. Ed. 2018, 57, 3806
W. He, J. Hu, P. Wang, L. Chen, K. Ji, S. Yang, Y. Li, Z. Xie, W. Xie
DOI: 10.1002/anie.201800567
CrossRef
chiral
racemic
Notes:
Alkaloids

Tubifolidine

C18H24N2 = 268
Angew. Chem. Int. Ed. 2018, 57, 3806
W. He, J. Hu, P. Wang, L. Chen, K. Ji, S. Yang, Y. Li, Z. Xie, W. Xie
DOI: 10.1002/anie.201800567
CrossRef
chiral
racemic
Notes:
Alkaloids

Parvineostemonine

C17H25NO2 = 275
Chem. Eur. J. 2018, 24, 3994
C. K. G. Gerlinger, S. Krüger, T. Gaich
DOI: 10.1002/chem.201800365
CrossRef
chiral
racemic
Notes:
Alkaloids

Lasubine Ⅱ

C17H25NO3 = 291
Org. Lett. 2018, 20, 1439
H. E. Ho, M. J. James, P. O’Brien, R. J. K. Taylor, W. P. Unsworth
DOI: 10.1021/acs.orglett.8b00225
CrossRef
chiral
racemic
Notes: formal synthesis
55 data found. 1 - 30 listed Next Last