Natural Products with Heterocyclic Ring System

Synthesis

New Heterocyclic Natural Products

Updated: 4 July, 2018

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose synthesis has been established.

94 data found. 1 - 30 listed Next Last
Polyketides

Phomonol. 4-epi-

C11H20O4 = 216
Tetrahedron Lett. 2017, 58, 3588
X. Wang, R. Feng, C. Qi, Z. Yang
DOI: 10.1016/j.tetlet.2017.07.066
CrossRef
chiral
racemic
Notes:
Polyketides

Ramariolide D

C16H24O3 = 264
Chemistry Lett. 2017, 46, 1409
M. Kuse, M. Moriguchi, M. Hachida, H. Takikawa
DOI: 10.1246/cl.170631
CrossRef
chiral
racemic
Notes:
Polyketides

Ramariolide C

C16H26O3 = 266
Chemistry Lett. 2017, 46, 1409
M. Kuse, M. Moriguchi, M. Hachida, H. Takikawa
DOI: 10.1246/cl.170631
CrossRef
chiral
racemic
Notes:
Polyketides

Obolactone

C19H18O4 = 310
Tetrahedron 2017, 73, 5547
R. N. Kumar, H. M. Meshram
DOI: 10.1016/j.tet.2017.08.001
CrossRef
chiral
racemic
Notes:
Polyketides

Aspicilin

C18H32O5 = 328
J. Org. Chem. 2017, 82, 9126
R. Schmidt, M. Ostermeier, R. Schobert
DOI: 10.1021/acs.joc.7b01702
CrossRef
chiral
racemic
Notes:
Polyketides

Lankacidinol

C25H35NO7 = 461
J. Am. Chem. Soc. 2017, 139, 12939
K. Zheng, D. Shen, R. Hong
DOI: 10.1021/jacs.7b08500
CrossRef
chiral
racemic
Notes:
Polyketides

Neomaclafungin A

C44H76O11 = 780
Chem. Asian J. 2017, 12, 2211
S. Zhu, Y. Wu
DOI: 10.1002/asia.201700950
CrossRef
chiral
racemic
Notes:
Aromatics

Armillariol C

C13H20O4 = 240
J. Nat. Prod. 2017, 80, 2561
M. D. Reddy, H. Kobori, T. Mori, J. Wu, H. Kawagishi, E. B. Watkins
DOI: 10.1021/acs.jnatprod.7b00484
CrossRef
chiral
racemic
Notes: synthesis of both enantiomer
Aromatics

Osthol

C15H16O3 = 244
Eur. J. Org. Chem. 2017, , 5204
D. Konrádová, H. Kozubíková, K. Doležal, J. Pospíšil
DOI: 10.1002/ejoc.201701021
CrossRef
chiral
racemic
Notes:
Aromatics

Coumestrol

C15H8O5 = 268
Tetrahedron 2017, 73, 5528
M. M. Naik, V. P. Kamat, S. G. Tilve
DOI: 10.1016/j.tet.2017.07.057
CrossRef
chiral
racemic
Notes:
Aromatics

Coumestrol, 4’-O-Methyl-

C16H10O5 = 282
Tetrahedron 2017, 73, 5528
M. M. Naik, V. P. Kamat, S. G. Tilve
DOI: 10.1016/j.tet.2017.07.057
CrossRef
chiral
racemic
Notes:
Aromatics

Lingzhiol

C15H14O6 = 290
J. Org. Chem. 2017, 82, 9844
L.-M. Mehl, M. E. Maier
DOI: 10.1021/acs.joc.7b01416
CrossRef
chiral
racemic
Notes:
Aromatics

Spiroxin C

C20H10O7 = 362
Angew. Chem. Int. Ed. 2017, 56, 11460
Y. Ando, A. Hanaki, R. Sasaki, K. Ohmori, K. Suzuki
DOI: 10.1002/anie.201705562
CrossRef
chiral
racemic
Notes:
Aromatics

Dracoflavan C1

C33H3,O6 = 522
Angew. Chem. Int. Ed. 2017, 56, 12332
M. Schmid, D. Trauner
DOI: 10.1002/anie.201705390
CrossRef
chiral
racemic
Notes:
Aromatics

Dracoflavan C2

C30H30O6 = 522
Angew. Chem. Int. Ed. 2017, 56, 12332
M. Schmid, D. Trauner
DOI: 10.1002/anie.201705390
CrossRef
chiral
racemic
Notes:
Aromatics

Myrtucommuacetalone

C39H54O9 = 666
Org. Lett. 2017, 19, 4786
H. Liu, L. Huo, B. Yang, Y. Yuan, W. Zhang, Z. Xu, S. Qiu, H. Tan
DOI: 10.1021/acs.orglett.7b02159
CrossRef
chiral
racemic
Notes:
Aromatics

Myrtucommulone J

C39H54O9 = 666
Org. Lett. 2017, 19, 4786
H. Liu, L. Huo, B. Yang, Y. Yuan, W. Zhang, Z. Xu, S. Qiu, H. Tan
DOI: 10.1021/acs.orglett.7b02159
CrossRef
chiral
racemic
Notes:
Aromatics

Dragonbloodin A2

C50H44O10 = 804
Angew. Chem. Int. Ed. 2017, 56, 12332
M. Schmid, D. Trauner
DOI: 10.1002/anie.201705390
CrossRef
chiral
racemic
Notes:
Aromatics

Dragonbloodin A1

C50H44O10 = 864
Angew. Chem. Int. Ed. 2017, 56, 12332
M. Schmid, D. Trauner
DOI: 10.1002/anie.201705390
CrossRef
chiral
racemic
Notes:
Terpenes

Pallescensin A

C15H22O = 218
Chem. Eur. J. 2017, 23, 13158
P. Alonso, P. Pardo, R. Fontaneda, F. J. Fañanás, F. Rodríguez
DOI: 10.1002/chem.201702490
CrossRef
chiral
racemic
Notes:
Terpenes

Heliannuol C

C15H20O3 = 248
Synth. Commun. 2017, 47, 1692
B. Biswas, P. K. Sen, A. Roy
DOI: 10.1080/00397911.2017.1344860
CrossRef
chiral
racemic
Notes:
Terpenes

Caparrapi Oxide, Bromo-epi-

C15H25OBr = 301
J. Am. Chem. Soc. 2017, 139, 13562
A. J. Burckle, B. Gál, F. J. Seidl, V. H. Vasilev, N. Z. Burns
DOI: 10.1021/jacs.7b07792
CrossRef
chiral
racemic
Notes:
Terpenes

Curcusone I

C20H26O3 = 314
Angew. Chem. Int. Ed. 2017, 56, 11624
Y. Li, M. Dai
DOI: 10.1002/anie.201706845
CrossRef
chiral
racemic
Notes: proposed structure
Terpenes

Curcusone J

C20H26O3 = 314
Angew. Chem. Int. Ed. 2017, 56, 11624
Y. Li, M. Dai
DOI: 10.1002/anie.201706845
CrossRef
chiral
racemic
Notes: proposed structure
Terpenes

Aplykurodinone-1

C20H30O3 = 318
Org. Lett. 2017, 19, 4861
B. Xu, W. Xun, T. Wang, F. G. Qiu
DOI: 10.1021/acs.orglett.7b02350
CrossRef
chiral
racemic
Notes:
Terpenes

EBC-329

C20H26O4 = 330
Org. Biomol. Chem. 2017, 15, 7102
T. J. Vanden Berg, D. M. Pinkerton, C. M. Williams
DOI: 10.1039/C7OB01400G
CrossRef
chiral
racemic
Notes: synthesis of enantiomer
Alkaloids

Kopsone

C11H19NO = 181
Angew. Chem. Int. Ed. 2017, 56, 11599
L. Zhai, X. Tian, C. Wang, Q. Cui, W. Li, S.-H. Huang, Z.-X. Yu, R. Hong
DOI: 10.1002/anie.201706018
CrossRef
chiral
racemic
Notes:
Alkaloids

Pyrrolallosedamine

C13H19NO = 205
Tetrahedron 2017, 73, 5344
V. A. Bhosale, S. B. Markad, S. B. Waghmode
DOI: 10.1016/j.tet.2017.07.023
CrossRef
chiral
racemic
Notes:
Alkaloids

Pyrrolsedamine

C13H19NO = 205
Tetrahedron 2017, 73, 5344
V. A. Bhosale, S. B. Markad, S. B. Waghmode
DOI: 10.1016/j.tet.2017.07.023
CrossRef
chiral
racemic
Notes: synthesis of both enantiomers
Alkaloids

Clausenol

C13H9NO2 = 227
Synthesis 2017, 49, 4357
R. I. Hernández-Benitez, D. Zárate-Zárate, F. Delgado, J. Tamariz
DOI: 10.1055/s-0036-1588467
CrossRef
chiral
racemic
Notes: formal synthesis
94 data found. 1 - 30 listed Next Last