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Note | Regular issue | Vol 53, No. 7, 2000, pp.1589-1593
Published online, 1st January, 1970
DOI: 10.3987/COM-00-8931
2,3-Dialkylchromones from Mycobiont Cultures of the Lichen Graphis scripta

Yukiko Takenaka, Takao Tanahashi,* Naotaka Nagakura, and Nobuo Hamada

*Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan


From the cultures of spore-derived mycobionts of lichen Graphis scripta, three chromones, 5-hydroxy-2,3-dimethyl-7-methoxychromone (1), 5-hydroxy-3-hydroxymethyl-2-methyl-7-methoxychromone (2), 5-hydroxy-2-hydroxymethyl-3-methyl-7-methoxychromone (3), were isolated. Compound (1) has been characterized as a natural product for the first time. The structures of two new chromones (2) and (3)were established on the basis of spectroscopic evidences. This is the first instance of isolation of 2,3-dialkylated chromones from lichen mycobionts.