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Note | Regular issue | Vol 55, No. 2, 2001, pp.371-376
Published online, 1st January, 1970
DOI: 10.3987/COM-00-9086
A Synthesis of Bipowine and Bipowinone

Somsak Ruchirawat* and Sunthorn Predapitakkun

*Labotratory of Medicinal Chemistry, Chulabhorn Reseach Institute, Vipavadee-Rangsit Highway, Bangkok 10210, Thailand

Abstract

Various oxidizing agents were investigated for the synthesis of bipowine (1) and bipowinone (2), two symmetrical dimeric aporphine alkaloids, from the oxidative coupling of dehydroaporphine (3).