Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Regular issue | Vol 55, No. 7, 2001, pp.1347-1363
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9215
Quinone-cyclized Porfiromycins

Younghwa Na and Harold Kohn*

*Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7360, U.S.A.

Abstract

Mitomycin C and porfiromycin cyclization has been implicated in the pathway for KW-2149 and BMS-181174 function. The importance of the porfiromycin C(7) structure and nucleophile for quinone cyclization was determined showing that both C(7) and C(8) annulation processes occur.