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Note | Regular issue | Vol 55, No. 12, 2001, pp.2397-2404
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9332
Bidirectional Conversion of Galanthamine and Crinine Type Heterocycles

Matthias Treu, Stefan Welzig, and Ulrich Jordis*

*Institute of Organic Chemistry, Vienna University of Technology, Getreidemarkt 9/154, A-1060 Vienna, Austria

Abstract

The conversion of galanthamine-type molecules into crinine-type compounds and vice versa has been accomplished by a ring opening-Michael addition-cascade of a galanthamine-type secondary amine and a crinine-type quarternary ammonium salt.