Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 57, No. 4, 2002, pp.637-648
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9429
Chemoselective Debezylation of the N-1-Phenylethyl Goup in 2-Oxazolidinones by the Anisole-Methanesulfonic Acid System

Shigeo Sugiyama, Kenji Morishita, Mariko Chiba, and Keitaro Ishii*

*Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

Abstract

The chemoselective removal of N-1-phenylethyl group in 2-oxazolidinones by the anisole–methanesulfonic acid system was investigated. Optically active 4,5-cis- and 4,5-trans-diphenyl-2-oxazolidinones (1a–d) were easily synthesized from dl-stilbene oxides (trans- and cis-7a) using this debenzylation.