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■ 1,3-Dipolar Cycloaddition Reactions to Galanthamine Nitrone: An Entry to 4a,5,9,10-Tetrahydro-6H,14aH-benzofuro[3a,3,2-ef]isoxazolo[3,2-a][2]benzazepines

Margit Hemetsberger, Matthias Treu, Christian Hametner, Ulrich Jordis, Kurt Mereiter, and Johannes Fröhlich*

*Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, A-1060 Vienna, Austria

Abstract

Starting with galanthamine nitrone as the 1,3-dipole derivatives of the novel 4a,5,9,10-tetrahydro-6H,14aH-benzofuro[3a,3,2-ef]isoxazolo[3,2-a][2]benzaz-epi-ne ring system have been prepared by cycloaddition.