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Paper | Regular issue | Vol 60, No. 5, 2003, pp.1095-1110
Published online, 3rd March, 2003
DOI: 10.3987/COM-02-9703
A Novel Substitution Reaction of Tetrahydropyrano[3,4-b]indole Derivative — Chain Extension and Structural Correlation Study

Shan-Yen Chou

*Development Center for Biotechnology, Hsi-Chih Research Park 101, Lane 169, Kang Ning St, Hsi Chih Cheng, Taipei Hsien, Taiwan, R.O.C.


An unusual cyanation with rearrangement of a 1-chloromethyl- tetrahydropyrano[3,4-b]indole-1-acetic acid ester derivative is reported. The resulting C-1 chain extension product is identified by correlation studies and spectral method.