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Communication | Special issue | Vol 58, No. 1, 2002, pp.47-51
Published online, 1st January, 1970
DOI: 10.3987/COM-02-S(M)10
Selective Synthesis of β-Amino Esters and β-Lactams by Rhodium-catalyzed Reformatsky-Type Reaction

Kazuo Kanai, Hitoshi Wakabayashi, and Toshio Honda*

*Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan


β-Amino esters and β-lactams are synthesized selectively from aldimines and ethyl bromoacetate by applying a simply modified rhodium-catalyzed Reformatsky-type reaction.