Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 60, No. 9, 2003, pp.2095-2101
Published online, 4th August, 2003
DOI: 10.3987/COM-03-9832
Synthesis of Naphth[3,2,1-cd]indole by Heck Cyclization of 2-Methoxycarbonyl-3-benzoylindoles

Yasuyoshi Miki,* Hideaki Shirokoshi, Mikito Asai, Yoshiyuki Aoki, and Hana Matsukida

*Faculty of Pharmaceutical Sciences, Kinki University, 3-4-1, Kowakae, Higashi-Osaka 577-8502, Japan

Abstract

Reaction of 1-benzylindole-2,3-dicarboxylic anhydride with 1,3-dimethoxybenzene in the presence of titanium(IV) chloride gave the corresponding 3-(2,4-dimethoxybenzoyl)indole-2-carboxylic acid as the sole product. This carboxylic acid could be converted to naphth[3,2,1-cd]indole.