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Note | Regular issue | Vol 60, No. 12, 2003, pp.2767-2773
Published online, 25th September, 2003
DOI: 10.3987/COM-03-9881
Four New Isoflavonoids and a New 2-Arylbenzofuran from the Roots of Erythrina variegata

Hitoshi Tanaka,* Miyuki Hirata, Hideo Etoh, Magoichi Sako, Masaru Sato, Jin Murata, Hiroko Murata, Dedy Darnaedi, and Toshio Fukai

*Faculty of Pharmacy, Meijo University, 150 Yagoto, Tempaku-ku, Nagoya, Aichi 468-8503, Japan

Abstract

Four new isoflavonoids, eryvarins H-K, and a new 2-arylbenzofuran, eryvarin L, together with five known compounds, were isolated from the roots of Erythrina variegata. Their structures were established on the basis of spectroscopic analysis. Eryvarins H and I are rare naturally-occurring isoflav-3-enes. The antibacterial activity of these five new compounds against 13 strains of methicillin-resistant Staphylococcus aureus (MRSA) was examined.