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Note | Regular issue | Vol 63, No. 2, 2004, pp.359-366
Published online, 15th December, 2003
DOI: 10.3987/COM-03-9922
Lipoxygenase Inhibiting Flavonoids from Indigofera hetrantha

Aziz-ur-Rehman, Abdul Malki,* Naheed Riaz, Habib Ahmad, Sarfraz Ahmad Nawaz, and Muhammad Iqubal Choudhary

*International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Pakistan


Hetranthins A (1) and B (2), new flavonoids, together with known compounds 7,3’,4’-trihydroxyflavanone (3) and 3,5,7,3’,4’-pentahydroxyflavanone (4) have been isolated from the ethyl acetate fraction of Indigofera hetrantha. Their structures have been assigned on the basis of spectral analysis. Compounds (1-4) showed inhibitory activity against lipoxygenase enzyme.