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Paper | Regular issue | Vol 63, No. 3, 2004, pp.609-629
Published online, 16th January, 2004
DOI: 10.3987/COM-03-9964
Synthesis of 5-Substituted Ethyl 3-Oxo-2H-pyrazolo[4,3-c]pyridine-7-carboxylates

David Bevk, Renata Jakse, Amalija Colobic, Ljubo Golic, Anton Meden, Jurij Svete,* and Branko Stanovnik*

*Faculty of Chemistry and Chemical Technology, University of Ljubljana, Askerceva 5, SI-1000 Ljubljana, Slovenia

Abstract

Ethyl (2E)-3-dimethylamino-2-[(4Z)-4-dimethylaminomethylidene-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]propenoate (3) was transformed with N-nucleophiles into ethyl 3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3—c]pyridine-7-carboxylates (6, 7, 9, 12, and 14).