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Communication | Special issue | Vol 62, No. 1, 2004, pp.207-211
Published online, 4th November, 2003
DOI: 10.3987/COM-03-S(P)52
Synthesis of New Potentially Antiviral Furan-fused Compounds by Thermolysis of Benzocyclobutene Derivatives

Yuji Matsuya, Hongbo Qin, Mamiko Nagaoka, and Hideo Nemoto*

*Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan


New potentially antiviral furan-fused tetracyclic compounds were prepared using intramolecular cycloaddition of o-quinodimethane generated by thermolysis of benzocyclobutene derivatives. It was found that the reaction course was changed depending on the length of alkyl chain connecting quinodimethane and furan ring.