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Communication | Special issue | Vol 61, No. 1, 2003, pp.19-22
Published online, 4th July, 2003
DOI: 10.3987/COM-03-S21
A Novel Ring Transformation of Nitropyrimidinone Leading to Polyfunctionalized Pyridones

Nagatoshi Nishiwaki,* Hiromi Morimura, Kazuo Matsushima, Mina Tamura, and Masahiro Ariga*

*Department of Chemistry, Osaka Kyoiku University, Asahigaoka, Kashiwara, Osaka 582-8582, Japan

Abstract

Polyfunctionalized 2-pyridones are readily prepared by the ring transformation using 3-methyl-5-nitropyrimidin-4(3H)-one with active methylene compounds in the presence of piperidine.