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Paper | Regular issue | Vol 63, No. 9, 2004, pp.2019-2032
Published online, 26th July, 2004
DOI: 10.3987/COM-04-10130
Synthesis of 2,3-Dihydro-4(1H)-quinazolinones

Jaime Escalante,* Patricia Flores, and Jaime M. Priego

*Chemical Research Center, Morelos Autonomous State University, Av. Universidad No. 1001, Colonia Chamilpa, C.P. 62210 Cuernavaca-Morelos, Mexico

Abstract

An improved procedure for the synthesis of 2-substituted 2,3-dihydro-4(1H)-quinazolinones through diastereomer separation of the corresponding quinazolinones derivatives is presented. The determination of their absolute configurations was obtained by X-Ray diffraction.