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Note | Regular issue | Vol 63, No. 10, 2004, pp.2371-2377
Published online, 27th August, 2004
DOI: 10.3987/COM-04-10142
Effect of Sodium Naphthalenide, a Key Set Reagent, on 3-Substituted Indoles

Avijit Banerji*, Debasish Bandyopadhyay, and Bidyut Basak

*Centre of Advanced Studies on Natural Products, Department of Chemistry, Calcutta University, 92, A. P. C Road, Kolkata 700009, India


Action of the single electron transfer (SET) reagent sodium naphthalenide on 3-substituted indoles revealed that indoles with electron-donating substituents do not respond whereas indoles with electron-withdrawing substituents easily react, yielding several products depending upon the substituent.