Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 65, No. 5, 2005, pp.1035-1049
Published online, 3rd March, 2005
DOI: 10.3987/COM-04-10246
Cu(I)-catalyzed Formation of D-Mannofuranosyl 1,4-Disubstituted 1,2,3-Triazolecarbohybrids

Penny L. Miner, Timothy R. Wagner, and Peter Norris*

*Department of Chemistry, Youngstown State University, 1 University Plaza, Youngstown, OH 44555-3663, U.S.A.


2,3:5,6-Di-O-isopropylidene-D-mannofuranose has been exploited as a platform for the synthesis of new 1,2,3-triazolecarbohybrids. Placement of an azide group at C-1 (and C-6) of the carbohydrate allows for reaction with various alkynes in the presence of a Cu(I) catalyst to generate 1,4-disubstituted triazoles regiospecifically. The use of sugar-derived alkynes leads to 1,2,3-triazole-linked di- and trisaccharide carbohybrid analogs with retention of the β-D-manno configuration.