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Note | Regular issue | Vol 65, No. 5, 2005, pp.1177-1181
Published online, 3rd March, 2005
DOI: 10.3987/COM-04-10312
A Green Approach to the Synthesis of 2,3-Dihydropyrimidin-2(1H)-ones by Uronium Hydrogensulfate under Solvent-free Conditions

Peyman Salehi,* Minoo Dabiri, Mohammad Ali Zolfigol, and Mostafa Baghbanzadeh

*Department of Phytochemistry, Aromatic and Medicinal Plants and Drug Research Institute, Shahid Beheshti University, Evin, Tehran 1983963113, Iran

Abstract

3,4-Dihydropyrimidin-2(1H)-ones and -thiones are synthesized in high yields by a one-pot condensation of an aldehyde, a β-dicarbonyl compound with hydrogensulfate salt of urea or thiourea under solvent-free conditions.