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Note | Regular issue | Vol 65, No. 8, 2005, pp.1985-1988
Published online, 28th June, 2005
DOI: 10.3987/COM-05-10451
An Efficient Synthesis of Bergapten

Kazuaki Oda,* Naozumi Nishizono, Yukio Tamai, Yuki Yamaguchi, Teruki Yoshimura, Keiji Wada, and Minoru Machida

*Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan


An efficient synthesis of the linear furanocoumarin, bergapten, is reported. In order to avoid the formation of the angular furanocoumarin, we have adopted iodine as protecting group at the 8 position of the coumarin ring.