Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Regular issue | Vol 65, No. 10, 2005, pp.2505-2511
Published online, 23rd August, 2005
DOI: 10.3987/COM-05-10496
Synthesis of Quinolyl- and Isoquinolyl Heteroarylamines Using Palladium Catalyzed Suzuki Cross-Coupling Reaction

Ihl Young Choi Lee,* Myung Hee Jung, Hee-Jeong Lim, and Hyo Won Lee*

*Medicinal Chemistry, Korea Research Institute of Chemical Technology, 100 Jang-dong, Yuseong, Daejon 305-600, Korea

Abstract

Quinolyl- and isoquinolylboronic acids are prepared from 5-bromoquinoline and 5-bromoisoquinoline, respectively, via halogen-metal exchange. Suzuki cross-coupling of these compounds with haloheteroarylamine leading to the corresponding heteroarylamine derivatives is described.