Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 68, No. 3, 2006, pp.475-481
Published online, 17th January, 2006
DOI: 10.3987/COM-05-10619
Copper Catalyzed Cyclopropanation of 1,2,3,4-Tetrahydropyridin-2-ones with Trimethylsilyldiazomethane: A Facile and Selective Synthesis of 2-Aza-3-oxobicyclo[4.1.0]heptanes

Vishal B. Sharma, Suman L. Jain, and Bir Sain*

*Chemical and Biotechnology Division, Indian Institute of Petroleum, Dehradun-248005, India

Abstract

The reactions of a series of 1,2,3,4-tetrahydropyridin-2-ones with trimethylsilyldiazomethane using catalytic amounts of copper(II) triflate in refluxing 1,2-dichloroethane yielded exclusively 3-oxo-2-azabicyclo[4.1.0]heptanes in good yields. The application of ultrasonic radiation enhanced the reaction rate and allowed the reactions to be conducted at room temperature.