Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Special issue | Vol 67, No. 1, 2006, pp.399-405
Published online, 15th July, 2005
DOI: 10.3987/COM-05-S(T)14
Formation of 4’,5’-Didehydro-5’-deoxy-3’-O-methyluridine via Regioselective Nucleophilic Addition of Methoxide Anion to 2’,3’-Anhydro-5’-dehydro-5’-iodouridine

Hironao Sajiki,* Hideki Takasu, and Kosaku Hirota*

*Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, 6-1 Mitahora-higashi 5-chome, Gifu 502-8585, Japan


Treatment of 2’,3’-anhydro-5’-deoxy-5’-iodouracil (1) with sodium methoxide regioselectively provided 4’,5’-didehydro-5’-deoxy-3’-O-methyluridine (2) as the sole product via 4’,5’-didehydro-5’-deoxy-2’,3’-epoxyuridine (6) as an intermediate.