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Note | Special issue | Vol 67, No. 1, 2006, pp.407-411
Published online, 15th July, 2005
DOI: 10.3987/COM-05-S(T)15
A Concise Synthesis of (+)-Indolizidine 209D Using a C2-Symmetric 2,6-Diallylpiperidine

Hiroki Takahata* and Motohiro Ichinose

*Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan

Abstract

An asymmetric synthesis of (+)-indolizidine 209D (2) using C2-symmetric 2,6-diallylpiperidine (1) as a chiral building block is presented in a straightforward fashion.