Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Special issue | Vol 67, No. 2, 2006, pp.777-784
Published online, 8th November, 2005
DOI: 10.3987/COM-05-S(T)49
Regioselective Synthesis of 4-Alkylpyridines from Pyridine and Aldehydes via Dipole Reversal Process of 1,4-Dihydropyridine Phosphonate

Phil Ho Lee,* Kooyeon Lee, Jun Hwan Shim, Seong Guk Lee, and Sundae Kim

*Department of Chemistry, Kangwon National University, Chuncheon, Kangwon 200-701, Korea


4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1,4-dihydropyridine phosphonate via phosphonioalkoxycarbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.