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Communication | Special issue | Vol 67, No. 2, 2006, pp.523-528
Published online, 30th September, 2005
DOI: 10.3987/COM-05-S(T)54
Synthesis of Bicyclic Compounds Containing a 2-Pyridone Structure by Addition Reactions of Malonic Esters to Alkynylpyridines, Pyrimidine, and Thiazoles

Iwao Hachiya, Masaki Atarashi, and Makoto Shimizu*

*Department of Chemistry for Materials, Faculty of Engineering, Mie University, 1515 Uehama-cho, Tsu, Mie 514-8507, Japan

Abstract

4H-Quinolizin-4-ones, 6H-pyrido[1,2-a]pyrimidin-6-ones, and 5H-thiazolo[3,2-a]pyridin-5-ones were prepared by addition reactions of malonic esters to 2-alkynylpyridines, pyrimidine, and thiazoles.