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Communication | Regular issue | Vol 68, No. 11, 2006, pp.2253-2257
Published online, 3rd October, 2006
DOI: 10.3987/COM-06-10871
Microwave-Assisted Cycloaddition Reaction of Azides to N-Substituted 2-Azabicyclo[2.2.1]hept-5-en-3-ones

Minoru Ishikura,* Miyako Hasunuma, Koji Yamada, and Reiko Yanada

*Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract

The reaction of N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-ones (ABH) (1) with azides (2,4) could be effected under microwave conditions, producing aziridine-fused ABH (3) and triazolines (5,6) in good yields.