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Paper | Regular issue | Vol 71, No. 1, 2007, pp.141-151
Published online, 5th December, 2006
DOI: 10.3987/COM-06-10923
The Selective Functionalization of Pyridazino[4,5-d]pyridazines Using Polar Organometallic Reagents

Tibor Zs. Nagy, Krisztián Lörincz, Antal Csámpai,* and András Kotschy*

*Institute of Chemistry, Eötvös Loránd University, Pázmány Péter s. 1/A, H-1117 Budapest, Hungary

Abstract

Selected pyridazino[4,5-d]pyridazine derivatives were reacted with polar organometallic reagents to result in the addition of the organic moiety onto the 5-position of the ring system with high selectivity.