HETEROCYCLES
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Note | Regular issue | Vol 71, No. 2, 2007, pp.437-444
Published online, 22nd December, 2006■ Diastereoselective Synthesis of Chiral Methyl 2-Piperidin-2-ylpropanoates
Published online, 22nd December, 2006
DOI: 10.3987/COM-06-10938
■ Diastereoselective Synthesis of Chiral Methyl 2-Piperidin-2-ylpropanoates
Jennifer Pereira, Sandrine Calvet-Vitale, Marie-Claude Fargeau-Bellassoued, Virginie Mouries-Mansuy, Corinne Vanucci-Bacqué,* and Gérard Lhommet*
*Laboratory of Organic Chemsitry, University of Paris VI, 4 Place Jussieu , F-75005 Paris Cedex 05, France
Abstract
We report the synthesis of methyl (2S, 2’R)-2-piperidin-2-ylpropanoate by the diastereoselective reduction of the tetrasubtituted double bond of piperidine β-enamino ester (1).
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