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Communication | Special issue | Vol 72, No. 1, 2007, pp.191-197
Published online, 6th February, 2007
DOI: 10.3987/COM-06-S(K)52
A Novel Indole Synthesis via Conjugate Addition of Pyrrolidine to o-Nitrophenylacetylenes

Hidetoshi Tokuyama, Takaki Makido, Yuki Han-ya, and Tohru Fukuyama*

*Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Abstract

A novel indole synthesis reaction by conjugate addition of pyrrolidine to o-nitrophenylacetylenes and subsequent reductive cyclization of o-nitroarylenamines was developed.