Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Special issue | Vol 70, No. 1, 2006, pp.509-517
Published online, 24th November, 2006
DOI: 10.3987/COM-06-S(W)54
Synthesis of a Stable Pyridyl Boronate and Its Reaction with Aryl and Heteroaryl Halides

Steven J. Durrant,* Joanne L. Pinder,* Jean-Damien Charrier, Juan-Miguel Jimenez, Guy Brenchley, Philip N. Collier, David Kay, Andrew Miller, Françoise Pierard, Sharn Ramaya, Shazia Sadiq, and Heather C. Twin

*Vertex Pharmaceuticals Limited, 88 Milton Park, Abingdon, Oxfordshire, OX14 4RY, U.K.


The synthesis and reaction of a versatile 5-pyridyl boronate is described. This intermediate can be used to synthesize a range of biologically interesting 2-(1H)-pyridones.