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Communication | Special issue | Vol 73, No. 1, 2007, pp.169-175
Published online, 3rd August, 2007
DOI: 10.3987/COM-07-S(U)14
High-Throughput Synthesis of Substituted Hydrazine Derivatives

Michio Kurosu,* Prabagaran Narayanasamy, and Dean C. Crick

*Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523-1682, USA

Abstract

Regioselective alkylations of the hydrazine derivatives are achieved by using the (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methoxycarboxyl resin. High-throughput synthesis of monosubstituted and 1,1-disubstituted hydrazine building blocks is described.