Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 74, No. 1, 2007, pp.177-183
Published online, 4th October, 2007
DOI: 10.3987/COM-07-S(W)43
Titanium Tetraiodide Promoted Reductive Opening of 2-(1-Benzyloxyiminoethyl)aziridines, Leading to Aza-Aldol Reaction

Makoto Shimizu,* Shuji Nishiura, and Iwao Hachiya

*Department of Chemistry for Materials, Faculty of Engineering, Mie University, 1577 Tsu, Mie 514-8507, Japan

Abstract

Reductive ring-opening of 2-(1-benzyloxyiminoethyl)aziridines was regioselectively carried out with titanium tetraiodide to form the titanium aza-enolates, which in turn were subjected to addition reaction with aldehydes to give aza-aldol products in good yields with high diastereoselectivities.