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Paper | Regular issue | Vol 75, No. 10, 2008, pp.2513-2521
Published online, 12th June, 2008
DOI: 10.3987/COM-08-11442
Friedländer Quinoline Synthesis Catalyzed by M(HSO4)n (M=Al, Mg, Ca) under Solvent-Free Conditions

Khodabakhsh Niknam,* Mohammad Ali Zolfigol, and Amin Dehghani

*Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran

Abstract

Polysubstituted quinolines were synthesized from the 2-aminobenzophenone, ethylacetoacetate or ketones in the presence of metal hydrogen sulfates [M(HSO4)n] in good to high yields at 70 °C under solvent-free conditions.