Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 76, No. 2, 2008, pp.1081-1085
Published online, 30th June, 2008
DOI: 10.3987/COM-08-S(N)123
Synthesis of Chiral Tetraaminophosphonium Chlorides from N-Boc α-Amino Acid Esters

Daisuke Uraguchi, Sawako Sakaki, Yusuke Ueki, Takaki Ito, and Takashi Ooi*

*Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan


Preparation of chiral tetraaminophosphonium chlorides of type 1 starting from N-Boc α-amino acid esters is described. Modified conditions for the displacement of the tertiary hydroxy group of the intermediary amino alcohol pave a way for the assembly of 1 with various geminal aromatic groups, particularly those having electron-withdrawing substituents.