Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Special issue | Vol 76, No. 2, 2008, pp.1171-1180
Published online, 22nd May, 2008
DOI: 10.3987/COM-08-S(N)76
Dimeric Flavans from Gambir and Their Structural Correlations with (+)-Catechin

Shoko Taniguchi, Kayo Kuroda, Kou-ichi Doi, Masahiro Tanabe, Takashi Shibata, Takashi Yoshida, and Tsutomu Hatano*

*Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tsushima, Okayama 700-8530, Japan


We isolated two new flavan dimers, gambirflavan D3 (10) and gambirflavan D4 (12), together with gambiriin A3 (11), from gambir, a hot-water extract of the leaves and young twigs of Uncaria gambir. Because their spectral analyses suggested that they are derived from catechin, we conducted a conversion reaction using (+)-catechin (1) to produce these dimers; another new flavan, gambirflavan D5 (13), was obtained as a product of this reaction. The structural relationship of these dimeric flavans with (+)-catechin (1) is discussed.