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Communication | Regular issue | Vol 27, No. 6, 1988, pp.1317-1319
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4503
Novel Mechanistic Aspects of the 4-Acyl-β-lactam Formation from 1,2-Iminoketones

Benito Alcaide, Gema Dominguez, Joaquin Plumet,* and Miguel A. Sierra

*Departamento de Química Orgánica, Facultad de Química, Universidad Complutense de Madridas, Ciudad Universitaria, E-28040 Madrid, Spain


On the basis of chemical and stereochemical evidence the course of the formation of 4-acyl-β-lactams from 1,2-iminoketones by reaction with the acyl chloride/Et3N system or with the preformed ketene is discussed.