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Communication | Regular issue | Vol 27, No. 6, 1988, pp.1321-1324
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4520
■ Alkaloid Synthesis Using Furopyridone as Synthon —Synthesis of Key Intermediates for the Syntheses of (±)-Quinine, (±)-Ajmalicine, and (±)-7-Demethyltecomanine—

Takeaki Naito, Okiko Miyata, and Ichiya Ninomiya*

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan

Abstract

Furopyridones (4a, b, and c) have been proved as the potential synthons for alkaloid synthesis from their facile conversion to the key intermediates (9e), (10e), and (13) for the synthesis of quinine, ajmalicine, and 7-demethyltecomanine.