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Communication | Special issue | Vol 28, No. 1, 1989, pp.43-46
Published online, 1st January, 1970
DOI: 10.3987/COM-88-S16
A Synthetic Approach to (±)-Vindoline

Kozo Shishido, Hironori Komatsu, Keiichiro Fukumoto,* and Tetsuiji Kametani

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


A synthesis of the potential intermediate of (±) vindoline was achieved from the isochromanone (6), which was obtained by thermolysis of the benzocyclobutene (5).